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Thromb Haemost 2022 Aug 16. Epub 2022 Aug 16.

Department of Clinical Pharmacology, Medical University of Vienna, Vienna, Austria.

Background: Alongside its original diagnostic intention, the International Society on Thrombosis and Haemostasis' Disseminated Intravascular Coagulation (DIC) score predicts mortality in various patient groups.

Objectives: We investigated whether coagulopathy quantified by the DIC score can predict 30-day mortality in patients with liver disease and low fibrinogen levels.

Methods: We retrospectively analyzed all patients admitted to the Vienna General Hospital between 2003-2014 with a fibrinogen level of <150 mg/dL, a history of liver disease, and ≥2 pathological DIC parameters. Read More

J Am Coll Radiol 2022 Aug 13. Epub 2022 Aug 13.

Department or Radiology; University of Washington, Seattle, WA.

Purpose: Advanced imaging exams of emergently transferred patients (ETP) are overread to various degrees by receiving institutions. The practical clinical impact of these second opinions has not been studied in the past. The purpose of this study is to determine if emergency radiology (ERad) overreads change emergency medicine decision making in the emergency department on ETP. Read More

Int J Radiat Oncol Biol Phys 2022 Aug 13. Epub 2022 Aug 13.

Cheeloo College of Medicine, Shandong University, Jinan, Shandong, China; Department of Radiation Oncology, Shandong Cancer Hospital and Institute, Shandong First Medical University and Shandong Academy of Medical Sciences, Jinan, Shandong, China. Electronic address:

Purpose: To investigate the predictive value of the cardiac substructures (CS) dosimetric parameters for cardiac toxicity after definitive radiotherapy in locally advanced esophageal cancer.

Methods And Materials: Between August 2010 and January 2016, 716 patients with stage II-III esophageal cancer receiving definitive radiotherapy at two institutions were divided into the training (n = 432) and external validation cohorts (n = 284). Dose-volume histogram parameters for the whole heart (WH) and CSs were extracted. Read More

J Arthroplasty 2022 Aug 13. Epub 2022 Aug 13.

Department of Orthopaedic Surgery, University of Virginia, 2280 Ivy Road Musculoskeletal Center, Charlottesville, VA 22903. Electronic address:

Background: Osteopetrosis is a rare, inherited disorder in which bone remodels to become pathologically dense. There has been a paucity of data evaluating medical and surgical complications following total hip arthroplasty (THA) and total knee arthroplasty (TKA) in this patient population. The objective of this study was to evaluate osteopetrosis as a potential risk factor for medical and surgical complications following THA and TKA. Read More

J Allergy Clin Immunol Pract 2022 Aug 13. Epub 2022 Aug 13.

Section of Allergy and Immunology, Dartmouth-Hitchcock Medical Center, Lebanon, NH, USA; Dartmouth Geisel School of Medicine, Hanover, NH, USA.

Background: The influence of allergist management on peanut allergy (PA)-related healthcare utilization is unknown.

Objective: To determine if allergist care lowers PA costs METHODS: IBM MarketScan® Commercial Claims and Encounters Database was analyzed for PA diagnosis/reaction-related codes (January 2010-June 2019) in patients ≤64 years, with demographically matched non-PA food allergy controls (NPAFAC). Outcomes were measured and compared 12 months pre/post first claim date. Read More