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J Rheumatol 2022 Aug 15. Epub 2022 Aug 15.

Rheumatology Department, Great Ormond Street Hospital for Children, London, United Kingdom (UK), Imperial College School of Medicine, London, UK, Department of Adolescent Rheumatology, University College London Hospitals NHS Foundation Trust, London, UK, Centre for Adolescent Rheumatology Versus Arthritis at University College London, University College London Hospital and Great Ormond Street Hospital, London, UK, National Institute for Health Research University College London Hospitals Biomedical Research Centre, London, UK, Infection, Immunity and Inflammation Research and Teaching Department, UCL Great Ormond Street Institute of Child Health, London, UK, Centre for Rheumatic Diseases, Kings College, London, UK, National Institute for Health Research Biomedical Research Centre, Great Ormond Street Hospital, London, UK. Corresponding author: Orcid ID - 0000-0001-9200-7450 Postal address: Dr. Kerstin Nott, Paediatric Rheumatology department Great Ormond Street Hospital for Sick Children, Great Ormond Street, London, WC1N 3JH, UK.

Objective: To describe the phenotype, disease course, and treatment of a large cohort of children with sarcoidosis.

Methods: Patients with biopsies consistent with sarcoidosis, performed between 2010 and 2020, were included. Patients' notes were reviewed retrospectively. Read More

Respirology 2022 Aug 15. Epub 2022 Aug 15.

Division of Pulmonary and Critical Care Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.

Background And Objective: Chronic mucus hypersecretion (CMH) is a clinical phenotype of COPD. This exploratory post hoc analysis assessed relationship between CMH status and treatment response in IMPACT.

Methods: Patients were randomized to once-daily fluticasone furoate/umeclidinium/vilanterol (FF/UMEC/VI) 100/62. Read More

Urology 2022 Aug 12. Epub 2022 Aug 12.

Pediatric Urology Associates, P.C. Tarrytown, NY, USA.

Objective: To present our experience in a single pediatric urology practice over a ten-year period with bladder tumors in the pediatric population in an effort to add to the relatively small amount of existing data. We hope to expand the community's knowledge of presentations, management and natural history of pediatric bladder tumors.

Methods: We retrospectively queried our electronic medical records for ICD-10 and CPT codes relevant for bladder tumors. Read More

Eur J Vasc Endovasc Surg 2022 Aug 12. Epub 2022 Aug 12.

Division of Vascular Surgery, University of Pittsburgh Medical Center, Pittsburgh, PA.

Objectives: Aortic aneurysms involving aortic arch vessels are anatomically unsuitable for standard thoracic endovascular repair (TEVAR) without cervical debranching of the arch vessels. We report three-year outcomes of a single-branched thoracic endograft, following previous publication of perioperative and one-year outcomes.

Design: This is a multicenter feasibility trial of the GORE® TAG® Thoracic Branch Endoprosthesis (TBE), a thoracic endovascular graft incorporating a single retrograde branch for aortic arch vessel perfusion. Read More

J Shoulder Elbow Surg 2022 Aug 12. Epub 2022 Aug 12.

Rothman Orthopaedic Institute at Thomas Jefferson University, Philadelphia, PA, USA. Electronic address:

Introduction: Tranexamic acid (TXA) has been used surgically to decrease blood loss. The ability of TXA to improve arthroscopic visualization and allow for reduction in pump pressure is unknown. The purpose of this study was to determine the effect of intravenous TXA on change in pump pressure and visualization during arthroscopic rotator cuff repair. Read More