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ESMO Open 2022 Aug 12;7(4):100524. Epub 2022 Aug 12.

GZA Ziekenhuizen Campus Sint-Vincentius, Medical Oncology, Antwerpen, Belgium.

PRECISION is an initiative from the Belgian Society of Medical Oncology (BSMO) in collaboration with several stakeholders, encompassing four programs that aim to boost genomic and clinical knowledge with the ultimate goal to offer patients with metastatic solid tumors molecularly guided treatments. The PRECISION 1 study has led to the creation of a clinico-genomic database. The Belgian Approach for Local Laboratory Extensive Tumor Testing (BALLETT) and GeNeo studies will increase the number of patients with advanced cancer that have comprehensive genotyping of their cancer. Read More

Nano Res 2022 Aug 4:1-10. Epub 2022 Aug 4.

The College of life science, Northwest University, Xi'an, 710069 China.

With the increasing global threat of various diseases and infections, it is essential to develop a fast, low-cost, and easy-to-use point-of-care testing (POCT) system for inspections at all levels of medical institutions and self-examination at home. In this work, gold magnetic nanoparticles (GMNPs) are used as the key material, and a rapid visual detection method is designed through integrating loop-mediated isothermal amplification (LAMP) and lateral flow assay (LFA) biosensor for detecting a variety of analytes which includes whole blood, buccal swabs, and DNA. It is worth to note that the proposed method does not need DNA extraction. Read More

Mitochondrial DNA B Resour 2022 8;7(8):1454-1456. Epub 2022 Aug 8.

Environment and Plant Protection Institute, Chinese Academy of Tropical Agricultural Sciences, Haikou, PR China.

Coffee is one of the most popular beverages around the world. As one of the best-known coffee species, Liberian coffee ( Bull ex Hiern 1876) has a high resistance to leaf rust, a devasting disease caused by . However, there are few reports on the systematic position and phylogenetic relationship of at the chloroplast (cp) genome level. Read More

Mol Phylogenet Evol 2022 Aug 10:107608. Epub 2022 Aug 10.

Parasitic Diseases Branch, Division of Parasitic Diseases and Malaria, Centers for Disease Control and Prevention, Atlanta, Georgia, USA. Electronic address:

Multi-locus sequence typing (MLST) is widely used to investigate genetic relationships among eukaryotic taxa, including parasitic pathogens. MLST analysis workflows typically involve construction of alignment-based phylogenetic trees - i.e. Read More

Anal Bioanal Chem 2022 Aug 13. Epub 2022 Aug 13.

Department of Medical Microbiology, Amsterdam UMC Location University of Amsterdam, Meibergdreef 9, Amsterdam, The Netherlands.

Early detection of bacterial transmission and outbreaks in hospitals is important because nosocomial infections can result in health complications and longer hospitalization. Current practice to detect outbreaks uses genotyping methods amplified fragment length polymorphism (AFLP) and whole genome sequencing (WGS), which are not suitable methods for real-time transmission screening of both susceptible and resistant bacteria. The aim was to assess the typing technique Fourier transform infrared (FTIR) spectroscopy as real-time screening method to discriminate large amounts of susceptible and resistant bacteria at strain level when there is no evident outbreak in comparison with the WGS reference. Read More