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Open Heart 2022 Aug;9(2)

School of Cellular and Molecular Medicine, Bristol Medical School, University of Bristol, Bristol, UK.

Objective: To estimate the incidence and HRs for bleeding for different dual antiplatelet therapies (DAPT) in a real-world population with acute coronary syndrome (ACS) undergoing percutaneous coronary intervention (PCI) in England.

Design: A retrospective, population-based cohort study emulating a target randomised controlled trial (tRCT).

Data Sources: Linked Clinical Practice Research Datalink (CPRD) and Hospital Episode Statistics (HES). Read More

J Shoulder Elbow Surg 2022 Aug 9. Epub 2022 Aug 9.

Medical University of South Carolina, Charleston, SC, USA. Electronic address:

Background: Total shoulder arthroplasty (TSA) is becoming an increasingly common surgical procedure for numerous shoulder conditions. The incidence of revision TSA is increasing due to the increase in primary TSA and the increased utilization of TSA in younger patients. Conducting revision TSA as an outpatient procedure would be beneficial in limiting expenditure and resource allocation but must show a similar complication profile compared to inpatient revision TSA in order to justify its clinical value. Read More

Ann Cardiothorac Surg 2022 Jul;11(4):426-435

Libin Cardiovascular Institute, University of Calgary, Calgary, Canada.

Background: Aortic wall remodelling in bicuspid aortic valve (BAV) patients is heterogeneous and characterized by elastin fiber breakdown alongside impaired biomechanics. However, the relationship between aortic histopathological changes and biomechanics are incompletely understood. We clarify the influence of elastin fiber integrity on ex vivo aortic wall mechanical properties in BAV patients, and explore the influence of patient age. Read More

Ann Cardiothorac Surg 2022 Jul;11(4):363-368

Department of Medical Research, The Mayo Clinic, Rochester, MN, USA.

Background: The true incidence of bicuspid valve-related aortic dissection (AD) is extremely difficult to ascertain. This review aimed to provide the reported cumulative incidence of bicuspid aortic valve (BAV)-related AD in actively monitored study populations.

Methods: Four electronic databases were used to perform literature searches. Read More

Ann Cardiothorac Surg 2022 Jul;11(4):389-401

Department of Cardiovascular Surgery, Marcus Valve Center, Piedmont Heart Institute, Atlanta, GA, USA.

Bicuspid aortic valve (BAV) disease is the most common form of congenital heart valve defect. It is associated with aortic stenosis (AS), aortic insufficiency, and aortopathy. Treatment of severe AS requires valve replacement which historically has been performed with surgical aortic valve replacement (SAVR). Read More