Search Our Scientific Publications & Authors

Thorax 2022 Aug 15. Epub 2022 Aug 15.

Cicely Saunders Institute of Palliative Care, Policy and Rehabilitation, King's College London, London, UK

Background: In advanced disease, breathlessness becomes severe, increasing health services use. Breathlessness triggered services demonstrate effectiveness in trials and meta-analyses but lack health economic assessment.

Methods: Our economic study included a discrete choice experiment (DCE), followed by a cost-effectiveness analysis modelling. Read More

Thorax 2022 Aug 15. Epub 2022 Aug 15.

COPD Foundation, Miami, Florida, USA.

The 2021 purchase of the respiratory pharmaceutical company Vectura by Phillip Morris International has been criticised by the public health and medical community, as a conflict of interest, with little input to date, from the patient community or the public. To address this gap, the COPD Foundation, along with global partners, surveyed 1196 people with chronic respiratory disease. 70% were bothered by a tobacco company making an inhaler to treat lung conditions and 48% reported that they would want to switch inhalers if they knew that a tobacco company made or sold their inhaler devices. Read More

J Rheumatol 2022 Aug 15. Epub 2022 Aug 15.

Rheumatology Department, Great Ormond Street Hospital for Children, London, United Kingdom (UK), Imperial College School of Medicine, London, UK, Department of Adolescent Rheumatology, University College London Hospitals NHS Foundation Trust, London, UK, Centre for Adolescent Rheumatology Versus Arthritis at University College London, University College London Hospital and Great Ormond Street Hospital, London, UK, National Institute for Health Research University College London Hospitals Biomedical Research Centre, London, UK, Infection, Immunity and Inflammation Research and Teaching Department, UCL Great Ormond Street Institute of Child Health, London, UK, Centre for Rheumatic Diseases, Kings College, London, UK, National Institute for Health Research Biomedical Research Centre, Great Ormond Street Hospital, London, UK. Corresponding author: Orcid ID - 0000-0001-9200-7450 Postal address: Dr. Kerstin Nott, Paediatric Rheumatology department Great Ormond Street Hospital for Sick Children, Great Ormond Street, London, WC1N 3JH, UK.

Objective: To describe the phenotype, disease course, and treatment of a large cohort of children with sarcoidosis.

Methods: Patients with biopsies consistent with sarcoidosis, performed between 2010 and 2020, were included. Patients' notes were reviewed retrospectively. Read More

J Rheumatol 2022 Aug 15. Epub 2022 Aug 15.

Department of Pediatrics, Emory University School of Medicine, Atlanta, Georgia; Francis I. Proctor Foundation for Research in Ophthalmology, and Department of Ophthalmology University of California, San Francisco, San Francisco, California; Department of Ophthalmology, University of Nebraska Medical Center, Omaha, Nebraska; Children's Healthcare of Atlanta, Atlanta, Georgia; Department of Ophthalmology, Stanford University, Stanford, California; Department of Genetics, Emory University School of Medicine, Atlanta, Georgia; Department of Global and Community Health, George Mason University, Fairfax, Virginia; Division of Rheumatology and Pediatric Ophthalmology, Cincinnati Children's Hospital Medical Center and Department of Pediatrics, University of Cincinnati, Cincinnati, Ohio, USA.C. McCracken and J.G. Shantha contributed equally to this work. Research reported in this manuscript was supported by the National Eye Institute (NEI) Award Number K23EY021760 (STAH), K23EY030159 ( JGS), and the Rheumatology Research Foundation. STAH is also supported by NEI R01EY030521. SP is supported in part by a grant from the Marcus Foundation Inc., Atlanta. SY is a consultant for Santen and Clearside Biomedical, unrelated to this study. KARS is a consultant for Accordant, unrelated to this study. SP serves on the Macrophage Activation Syndrome Adjudication Committee for Novartis and is a Doximity Op-Med Fellow for 2021-22, unrelated to this study. The remaining authors declare no conflicts of interest relevant to this article. Address correspondence to Dr. S.T. Angeles-Han, Division of Rheumatology, Cincinnati Children's Hospital Medical Center, 3333 Burnett Avenue, Cincinnati, OH 45229, USA; Department of Pediatrics, University of Cincinnati, Cincinnati, OH 45229, USA. Email:

Pediatric chronic noninfectious uveitis (NIU) can lead to sight-threatening complications and often requires long-term immunosuppression. Uveitis occurs in isolation (ie, idiopathic NIU), or is associated with systemic diseases, most commonly juvenile idiopathic arthritis (JIA). Read More

Respirology 2022 Aug 15. Epub 2022 Aug 15.

Division of Pulmonary and Critical Care Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.

Background And Objective: Chronic mucus hypersecretion (CMH) is a clinical phenotype of COPD. This exploratory post hoc analysis assessed relationship between CMH status and treatment response in IMPACT.

Methods: Patients were randomized to once-daily fluticasone furoate/umeclidinium/vilanterol (FF/UMEC/VI) 100/62. Read More