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J Med Virol 2022 Aug 16. Epub 2022 Aug 16.

Department of Epidemiology and Biostatistics, School of Public Health, Anhui Medical University, 81 Meishan Road, Hefei, Anhui, China.

Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) infection can cause Corona Virus Disease 2019 (COVID-19), an acute respiratory inflammation that has emerged worldwide since December 2019, and it quickly became a global epidemic. Inflammatory bowel disease (IBD) is a group of chronic nonspecific intestinal inflammatory diseases whose etiology has not been elucidated. The two have many overlapping symptoms in clinical presentation, such as abdominal pain, diarrhea, pneumonia, etc. Read More

Am J Gastroenterol 2022 Aug 12. Epub 2022 Aug 12.

Institute for Health Science, MIKI Corporation, Nishinomiya, Hyogo, Japan.

Objectives: To determine the effectiveness of prune juice on chronic constipation.

Methods: We conducted a double-blind, randomized, placebo-controlled trial in Japanese subjects with chronic constipation.

Results: Prune intake significantly decreased hard and lumpy stools, while increasing normal stool and not increasing loose and watery stools. Read More

Eur J Oncol Nurs 2022 Aug 2;60:102186. Epub 2022 Aug 2.

University of Kentucky, College of Medicine, Department of Internal Medicine, Medical Oncology, Markey Cancer Center, 800 Rose Street, Lexington, KY, 40536, USA. Electronic address:

Purpose: The purpose of this study was to evaluate use of a proprietary amino acid-oral rehydration solution (AA-ORS) known as Enterade® to reduce the severity of chemotherapy related diarrhea (CRD), to improve patient reported Quality of Life (QOL), and to reduce treatment holds, delays, dose modifications, prevention of weight loss, and subjective improvement of associated gastrointestinal mucositis physical symptoms.

Methods: An experimental pilot study without randomization in a single population with two separate measurements over time was performed in a National Cancer Institute (NCI) designated cancer center in the South-Central United States. The variables included sociodemographic data, cancer diagnosis, chemotherapy treatment regimens, Common Terminology Criteria for Adverse Events (CTCAE) v5. Read More

Ther Adv Chronic Dis 2022 9;13:20406223221116798. Epub 2022 Aug 9.

Department of Pediatrics, Faculty of Medicine, King Abdulaziz University, P.O. Box 80205, Jeddah 21589, Saudi Arabia.

Interleukin-2 receptor alpha () defect (OMIM- # 606367) is an immune disease where affected patients are vulnerable to developing recurrent microbial infections in addition to lymphadenopathy and dermatological manifestations. This condition is known to be caused by pathogenic variants in the gene, which are inherited in an autosomal recessive fashion. In this case report, we present a patient with defect from Saudi Arabia who presented with chronic diarrhea, poor weight gain, mild villous atrophy, malnutrition, hepatomegaly, nonspecific inflammation, and an eczematous skin rash. Read More

Cureus 2022 Jul 11;14(7):e26757. Epub 2022 Jul 11.

Internal Medicine, Edward W (EW) Sparrow Hospital, Lansing, USA.

Late diagnosis of light chain (AL) amyloidosis can lead to catastrophic consequences on the quality of life of affected patients and overall disease prognosis. Therefore, clinicians should have high suspicion and recognize clinical red flags for amyloidosis. This case report presents a 65-year-old female who presented to the emergency department with chronic diarrhea and significant weight loss with significant hypotension. Read More