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Pre- and post-operative mechanical circulatory support in surgical repair of post-acute myocardial infarction mechanical complications.

Authors:
Anju Bhardwaj Sachin Kumar Ismael A Salas de Armas Angelo Nascimbene Sriram Nathan Biswajit Kar Igor D Gregoric

Ann Cardiothorac Surg 2022 May;11(3):304-309

The University of Texas Health Science Center at Houston, Houston, TX, USA.

The outcomes of patients with acute myocardial infarctions (AMI) have significantly improved with advances in early reperfusion strategies; however, patients with massive infarcts or those who do not receive timely revascularization may develop mechanical complications of AMI. The most common mechanical complications are ventricular septal rupture (VSR), acute mitral regurgitation (MR) due to papillary muscle rupture, and free-wall rupture. Each complication is associated with a high risk of morbidity and mortality, and requires a multidisciplinary approach for prompt diagnosis and hemodynamic stabilization. Surgery is the mainstay of therapy but is associated with poor outcomes if performed too early during the treatment course for VSR or if performed too late with MR and free wall rupture. Optimal timing for surgery in combination with temporary circulatory support may be a feasible strategy for better results.

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http://dx.doi.org/10.21037/acs-2021-ami-206DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9207699PMC
May 2022

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