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J Gastrointest Oncol 2022 Jun;13(3):1413-1422

Department of Gastrointestinal Oncology, H. Lee Moffitt Cancer Center & Research Institute, Tampa, FL, USA.

Background: Recommendations for postoperative surveillance and adjuvant therapy following curative-intent resection for biliary tract cancers-including intrahepatic and extrahepatic cholangiocarcinoma (IHCCA and EHCCA) and primary gallbladder cancer (GBC)-are uniform across primary tumor site. However, these tumors may have distinct patterns of recurrence.

Methods: A retrospective observational cohort study was performed at a specialty cancer center. Read More

World J Surg Oncol 2022 Jun 9;20(1):190. Epub 2022 Jun 9.

Department of General Surgery, The First Affiliated Hospital of Henan University of Science and Technology, 24 Jinghua road, Luoyang, 471000, China.

Background: Hepatopancreaticoduodenectomy (HPD) is one of the most complex procedures, and it is very rarely reported. Laparoscopic HPD (LHPD) is even rarer. To date, there are only 3 reports of LHPD for locally advanced gallbladder cancer (GBC) or extrahepatic cholangiocarcinoma (ECC). Read More

Mol Biol Rep 2022 Feb 5;49(2):1295-1301. Epub 2022 Jan 5.

Key Laboratory of Liver Transplantation, NHC Key Laboratory of Living Donor Liver Transplantation (Nanjing Medical University), Hepatobiliary Center, The First Affiliated Hospital of Nanjing Medical University, Chinese Academy of Medical Sciences, Nanjing, Jiangsu Province, China.

Background: Comprehensive genomic analysis of paired primary tumors and their metastatic lesions may provide new insights into the biology of metastatic processes and therefore guide the development of novel strategies for intervention. To date, our knowledge of the genetic divergence and phylogenetic relationships in gallbladder cancer (GBC) is limited.

Methods: We performed whole exome sequencing for 5 patients with primary tumor, metastatic lymph node (LNM) and corresponding normal tissue. Read More

AME Case Rep 2021 25;5:21. Epub 2021 Jul 25.

Medical Oncology Unit, Belcolle Hospital, ASL Viterbo, Viterbo, Italy.

Gallbladder cancer (GBC) is associated with a poor prognosis. Colonic metastases representing approximately 1% of total colorectal cancers, are very rarely reported. According to more recent data in the literature, cases of colon metastases from GBC have not been reported. Read More

Cureus 2019 Jul 28;11(7):e5258. Epub 2019 Jul 28.

Radiation Oncology, British Columbia Cancer Agency - Vancouver Cancer Centre, Vancouver, CAN.

Gallbladder carcinoma (GBC) metastasis to the uterine cervix is very rare, accounting for less than 10 reported cases. GBC is an uncommon neoplasm with a poor prognosis. Many patients remain asymptomatic until it reaches an advanced stage or discovered incidentally. Read More