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Case Report: Adrenocortical Oncocytoma in a Patient with a Previous Contralateral Adrenalectomy for a Cortisol-Secreting Adenoma.

Authors:
Letizia Canu Giuliano Perigli Benedetta Badii Raffaella Santi Gabriella Nesi Silvia Pradella Mario Maggi Alessandro Peri

Front Surg 2022 19;9:897967. Epub 2022 May 19.

Endocrinology, Department of Experimental and Clinical Biomedical Sciences 'Mario Serio', University of Florence, Florence, Italy.

Background: Oncocytomas are uncommon benign tumors that arise in various organs and are predominantly composed of oncocytes. Adrenocortical oncocytomas are extremely rare and are generally non-functioning.

Methods: We report the case of a 40-year-old patient with a progressively enlarging left adrenal mass. At the age of 19 he had undergone right adrenalectomy for a cortisol-secreting adenoma. Radiologic features were not typical of an adenoma and positive uptake was detected at F-FDG-PET. Because of the uncertain nature of the growing lesion, it was decided to proceed to surgical resection.

Results: The surgeon managed to remove the left adrenal mass, sparing the normal adrenal gland, and histology was consistent with adrenocortical oncocytoma. Corticosteroid supplementation was prescribed, but at reassessment, adrenal function was found to be preserved and treatment withdrawn.

Conclusions: Adrenal oncocytoma is a rare diagnosis, but should be considered in the presence of a growing mass with non-specific radiologic appearance.

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Source
http://dx.doi.org/10.3389/fsurg.2022.897967DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9160572PMC
May 2022

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