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A Pseudotumor.

Authors:
Jennifer Tat Jane Plitman Wayne L Gold

Am J Med 2022 May 27. Epub 2022 May 27.

Department of Medicine, University of Toronto, Ont, Canada; Division of Infectious Diseases, University Health Network, Toronto, Ont, Canada; Division of General Internal Medicine, University Health Network, Toronto, Ont, Canada.

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http://dx.doi.org/10.1016/j.amjmed.2022.05.005DOI Listing
May 2022

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Multimodality imaging features of USP6-associated neoplasms.

Authors:
Stephen M Broski Doris E Wenger

Skeletal Radiol 2022 Aug 13. Epub 2022 Aug 13.

Department of Radiology, Mayo Clinic, Charlton Building North, 1st Floor, 200 First Street SW , Rochester, MN, 55905, USA.

Since the discovery of USP6 gene rearrangements in aneurysmal bone cysts nearly 20 years ago, we have come to recognize that there is a family of USP6-driven mesenchymal neoplasms with overlapping clinical, morphologic, and imaging features. This family of neoplasms now includes myositis ossificans, aneurysmal bone cyst, nodular fasciitis, fibroma of tendon sheath, fibro-osseous pseudotumor of digits, and their associated variants. While generally benign and in many cases self-limiting, these lesions may undergo rapid growth, and be confused with malignant bone and soft tissue lesions, both clinically and on imaging. Read More

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August 2022
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Evaluation of Orbital Lymphoproliferative and Inflammatory Disorders by Gene Expression Analysis.

Authors:
Karim Al-Ghazzawi Sven Holger Baum Roman Pförtner Svenja Philipp Nikolaos Bechrakis Gina Görtz Anja Eckstein Fabian D Mairinger Michael Oeverhaus

Int J Mol Sci 2022 Aug 3;23(15). Epub 2022 Aug 3.

Department of Ophthalmology, University Hospital Essen, 45147 Essen, Germany.

Non-specific orbital inflammation (NSOI) and IgG4-related orbital disease (IgG4-ROD) are often challenging to differentiate. Furthermore, it is still uncertain how chronic inflammation, such as IgG4-ROD, can lead to mucosa-associated lymphoid tissue (MALT) lymphoma. Therefore, we aimed to evaluate the diagnostic value of gene expression analysis to differentiate orbital autoimmune diseases and elucidate genetic overlaps. Read More

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August 2022
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Shifting gears to differentiation agents in acute promyelocytic leukemia with resource constraints-a cohort study.

Authors:
Tejasvini Vaid Mukul Aggarwal Jasmita Dass Rishi Dhawan Pradeep Kumar Ganesh Kumar Viswanathan Seema Tyagi Tulika Seth Manoranjan Mahapatra

Acta Oncol 2022 Aug 11:1-6. Epub 2022 Aug 11.

Department of Hematology, All India Institute of Medical Sciences, New Delhi, India.

Background: Treatment of acute promyelocytic leukaemia has emerged as a major success in hemato-oncology. While literature from the developed world boasts of outstanding outcomes, there is a paucity of data from the developing world. This study aimed to assess complications and outcomes of acute promyelocytic leukaemia in a resource-constrained setting. Read More

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August 2022
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[Pseudotumor cerebri in children and adolescents at the Saarland University Medical Center: a retrospective study].

Authors:
Melanie Freudenberg Marina Flotats-Bastardas Michael Zemlin Martin Poryo Sascha Meyer

Wien Med Wochenschr 2022 Aug 8. Epub 2022 Aug 8.

Klinik für Allgemeine Pädiatrie und Neonatologie, Universitätsklinikum des Saarlandes, Kirrberger Str., Geb. 9, 66421, Homburg, Deutschland.

Pseudotumor cerebri (PTC) is defined as a rare disease with a pathological increase in intracranial pressure of unknown origin. The aim of this retrospective study was to establish a uniform diagnostic and therapeutic protocol for children and adolescents for the Saarland University Medical Center. Data from 28 patients with pseudotumor cerebri aged 0-17 years in the period 2008-2018 were retrospectively collected and statistically analyzed. Read More

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August 2022
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Hemophilia A developing cerebral infarction after surgical treatment of giant hemophilic pseudotumor: a case report.

Authors:
Yiqing Ling Zhenyu Shi Chenying Su Xiaochen Liu Lingxin Zheng Xiaohao Pan Yan Sun Xuan Zhang Jinling Wei Ju Li Peijian Tong Taotao Xu

BMC Surg 2022 Aug 6;22(1):303. Epub 2022 Aug 6.

The First Affiliated Hospital of Zhejiang, Chinese Medical University, You Dian Road No.54, Hangzhou, 310006, Zhejiang Province, People's Republic of China.

Background: Cerebral infarction (CI) is an unusual complication in patients with bleeding disorders. To our knowledge, this is the first case of postoperative internal border-zone infarction (I-BZI) from Hemophilia A.

Case Presentation: We present a case of Hemophilia A developing I-BZI, after surgical treatment of giant hemophilic pseudotumor. Read More

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August 2022
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