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Retin Cases Brief Rep 2022 Aug 12. Epub 2022 Aug 12.

Department of Ophthalmology, Wake Forest University School of Medicine, Winston-Salem, NC.

Purpose: To describe two cases of traumatic lens subluxation resulting from pickleball injury.

Methods: Case series.

Results: A 77-year-old man presented with worsening vision and was noted to have subluxation of his intraocular lens 10 days after being struck in the eye with a pickleball. Read More

Retina 2022 Aug 12. Epub 2022 Aug 12.

Department of Ophthalmology, Medical University of Vienna, Währinger Gürtel 18-20, 1090 Vienna, Austria.

Purpose: To investigate the impact of baseline vitreomacular interface (VMI) status on treatment outcomes in patients treated with three different anti-vascular endothelial growth factors (anti-VEGF) for diabetic macular edema (DME).

Methods: Post-hoc analysis from patients enrolled in the DRCR.net Protocol T study. Read More

Evid Based Complement Alternat Med 2022 1;2022:4127293. Epub 2022 Aug 1.

Department of Ophthalmology, Clinical Medical College, Yangzhou University, Yangzhou 225000, Jiangsu, China.

For verifying the prognosis of Lucentis-assisted vitrectomy (PPV) in diabetic retinopathy (DR) and neovascular glaucoma (NVG), a retrospective analysis of DR and NVG patients who were admitted to our hospital from July 2019 to December 2020 was conducted. According to the treatment protocol, subjects who had PPV intervention were in the control group (CG;  = 38) and those receiving Lucentis adjunctive PPV were included in the intervention group (RG;  = 40). The indicators between groups were listed: treatment success rate, postoperative complication rate, surgical outcome indicators, BCVA, intraocular pressure (IOP) change, foveal thickness, and VEGF level in aqueous humor. Read More

Front Immunol 2022 25;13:941982. Epub 2022 Jul 25.

Department of Ophthalmology, Inner Mongolia Baogang Hospita, Baotou, Inner Mongolia, China.

Micro ribonucleic acids (miRNAs), as a category of post-transcriptional gene inhibitors, have a wide range of biological functions, are involved in many pathological processes, and are attractive therapeutic targets. Considerable evidence in ophthalmology indicates that miRNAs play an important role in diabetic retinopathy (DR), especially in inflammation, oxidative stress, and neurodegeneration. Targeting specific miRNAs for the treatment of DR has attracted much attention. Read More

Front Physiol 2022 25;13:961386. Epub 2022 Jul 25.

College of Medicine and Biological Information Engineering, Northeastern University, Shenyang, Liaoning, China.

Diabetic retinopathy (DR) and age-related macular degeneration (AMD) are forms of degenerative retinal disorders that may result in vision impairment or even permanent blindness. Early detection of these conditions is essential to maintaining a patient's quality of life. The fundus photography technique is non-invasive, safe, and rapid way of assessing the function of the retina. Read More