Background: To examine the influence of mouth breathing on maxillofacial and airway development in children and adolescents with different cervical vertebral maturation stages.Methods: Lateral cephalometric radiograph of a total of 120 children and adolescents, 64 girls and 56 boys (7-15 years old), diagnosed with mouth breathing were examined. Maxillofacial hard tissue, soft tissue and airway measurements were obtained using both manual and digital techniques.