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Vitam Horm 2022 10;120:271-288. Epub 2022 Jul 10.

Department of General and Endocrine Surgery, University Hospitals Cleveland, OH, Professor of Surgery, Case Western Reserve School of Medicine, Cleveland, OH, United States. Electronic address:

The history and evolution of parathyroid hormone is a true testament to inter-disciplinary collaboration among anatomists, biochemists and surgeons. The parathyroid glands were the last endocrine glands to be discovered in the mid-1800s. Over the next century, progress in the evaluation of primary hyperparathyroidism, the identification of parathyroid hormone (PTH) and its application for use in the field of parathyroid surgery have led to a significant improvement in surgical cure rates, accompanied by a shift toward minimally invasive surgical options. Read More

Cir Cir 2022 ;90(S1):45-51

Endocrinology and Metabolism Clinic, Sakarya University Medical Faculty, Sakarya. Turkey.

Objective: Voice quality disorders remain a problem with classical surgical method which is expected to decrease with new minimally invasive methods. We aimed to examine whether there is an impairment in voice quality among our patients who have undergone open minimally invasive parathyroid surgery.

Methods: Forty-seven primer hyperparathyroidism patients included in the study. Read More

Front Med (Lausanne) 2022 22;9:876692. Epub 2022 Jul 22.

Xinjiang Clinical Research Center for Kidney Disease, Division of Nephrology, Department of Internal Medicine, People's Hospital of Xinjiang Uygur Autonomous Region, Urumqi, China.

End-stage renal disease (ESRD) is a global health problem with a high incidence (1) and a steadily increasing prevalence (2). Secondary hyperparathyroidism (SHPT) is a common and serious complication of chronic renal failure (CRF) in dialysis patients (3). It is mainly manifested as parathyroid hyperplasia caused by abnormal calcium and phosphorus metabolism and active vitamin D resistance, resulting in excessive secretion of parathyroid hormone (PTH), which leads to complications such as bone deformity, osteoarthralgia, pruritus, ectopic calcification, and cardiovascular calcification in CKD patients, significantly reducing the quality of life in CKD patients (4, 5). Read More

J Am Coll Surg 2022 Aug 20;235(2):332-339. Epub 2022 Apr 20.

From Department of Surgery, Harvard Medical School, Boston, MA (Broekhuis, Cloonan, Sacks, James).

Background: Four-dimensional (4D) CT localization allows minimally invasive parathyroidectomy as treatment for primary hyperparathyroidism (PHPT), but false positive localization is frequent. We sought to characterize the ability of 4D CT to predict four-gland hyperplasia (HP) based on the size of candidate lesions.

Study Design: We retrospectively analyzed patients with PHPT who underwent 4D CT imaging and parathyroidectomy between 2014 and 2020 from a prospectively collected institutional database. Read More

Cureus 2022 Jul 5;14(7):e26576. Epub 2022 Jul 5.

Urology, Wythenshawe Hospital, Manchester, GBR.

Introduction Hypocalcemia following parathyroidectomy can often be problematic, requiring long-term follow-up. This complication can be permanent or transient. It most commonly occurs following head and neck surgery where there is accidental removal of the parathyroid gland or damage to the blood supply to the gland during dissection. Read More