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Diabetes Metab Res Rev 2022 Aug 7:e3569. Epub 2022 Aug 7.

Infectious Diseases Department, Gustave Dron Hospital, 59200, Tourcoing, France.

This article is protected by copyright. All rights reserved. This article is protected by copyright. Read More

Ann Saudi Med 2022 Jul-Aug;42(4):223-228. Epub 2022 Aug 4.

From the College of Pharmacy and College of Medicine, Alfaisal University. Riyadh, Saudi Arabia.

Background: The rate of severe acute respiratory syndrome coronavirus 2 (SARS CoV-2) infection and immunogenicity of a single dose of ChAdOx1 vaccine at 16 weeks post-vaccination among young and healthy participants remains unclear in Saudi Arabia.

Objectives: Assess the rate of subsequent infection and immunogenicity of a single dose of ChAdOx1 vaccine at 16 weeks post-vaccination in a sample of healthy and young participants.

Design: Cross-sectional study SETTING: Academic teaching hospital in Riyadh, Saudi Arabia SUBJECTS AND METHODS: Healthy participants 18-50 years of age, who received one dose of ChAdOx1 vaccine and had no history of SARS CoV-2 infection were recruited, and blood samples were obtained 16 weeks after vaccination to assess immunogenicity using a commercially available kit. Read More

Metabolomics 2022 Aug 7;18(8):67. Epub 2022 Aug 7.

Institute of Biology, Leiden University, Sylviusweg 72, 2333 BE, Leiden, The Netherlands.

Introduction: The leptin signaling pathway plays an important role as a key regulator of glucose homeostasis, metabolism control and systemic inflammatory responses. However, the metabolic effects of leptin on infectious diseases, for example tuberculosis (TB), are still little known.

Objectives: In this study, we aim to investigate the role of leptin on metabolism in the absence and presence of mycobacterial infection in zebrafish larvae and mice. Read More

Parasit Vectors 2022 Aug 6;15(1):283. Epub 2022 Aug 6.

Chinese Center for Disease Control and Prevention (Chinese Center for Tropical Diseases Research), NHC Key Laboratory of Parasite and Vector Biology, National Institute of Parasitic Diseases, WHO Collaborating Centre for Tropical Diseases, National Center for International Research On Tropical Diseases, Joint Research Laboratory of Genetics and Ecology On Parasite-Host Interaction, Chinese Center for Disease Control and Prevention & Fudan University, NO. 207 Ruijin 2nd Road, Huangpu District, Shanghai, People's Republic of China.

Background: Severe fever with thrombocytopenia syndrome (SFTS), one kind of tick-borne acute infectious disease, is caused by a novel bunyavirus. The relationship between meteorological factors and infectious diseases is a hot topic of current research. Liaoning Province has reported a high incidence of SFTS in recent years. Read More

Commun Biol 2022 Aug 6;5(1):790. Epub 2022 Aug 6.

Precision Vaccines Program, Division of Infectious Diseases, Boston Children's Hospital, Boston, MA, USA.

The SARS-CoV-2 Omicron variant evades vaccine-induced immunity. While a booster dose of ancestral mRNA vaccines effectively elicits neutralizing antibodies against variants, its efficacy against Omicron in older adults, who are at the greatest risk of severe disease, is not fully elucidated. Here, we evaluate multiple longitudinal immunization regimens of mRNA BNT162b2 to assess the effects of a booster dose provided >8 months after the primary immunization series across the murine lifespan, including in aged 21-month-old mice. Read More