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Rev Esp Patol 2022 Jul-Sep;55(3):156-162. Epub 2022 Apr 25.

BIOPAT, Biopatologia Molecular SL, Grup Assistència, Avenida Diagonal, 660, 08034, Barcelona, Spain; Histopat Laboratoris SL, Calle Mendel, 1, 08034, Barcelona, Spain; SCIAS-Hospital de Barcelona, Grup Assistència, Avenida Diagonal, 660, 08034, Bracelona, Spain.

Introduction: Analysis of circulating tumor DNA (ctDNA), also known as liquid biopsy, has been postulated to be a useful test in the prognostication, molecular profiling, and monitoring of cancer patients. In this series we aimed to analyze the concordance between the mutation status of formalin-fixed paraffin-embedded (FFPE) tumor samples and matched ctDNA, considering tumor molecular profiling as the gold standard technique.

Methods: This retrospective study included cancer patients with complete diagnostics and gene mutations detected in a previous FFPE tumor tissue Next-Generation Sequencing (NGS) study with a matched frozen plasma sample available for an NGS ctDNA assay. Read More

Int J Radiat Oncol Biol Phys 2022 Jun 29. Epub 2022 Jun 29.

Division of Cancer Care and Epidemiology, Cancer Research Institute at Queen's University, 10 Stuart Street, 2nd Level, Kingston, ON K7L3N6, Canada. Electronic address:

Background: Ensuring optimal access to radiotherapy (RT) facilities is challenging for many countries. External beam RT and brachytherapy (BCT) are required to treat advanced cervical cancer. In this analysis, we evaluate the system-level capacity of brachytherapy in Brazil and its relationship with access to complete cervix cancer radiation treatment with both external beam radiotherapy and BCT. Read More

Complement Ther Med 2022 Jun 29:102848. Epub 2022 Jun 29.

Department of Anesthesiology, Affiliated Hospital of Jiaxing University, The First Hospital of Jiaxing, Jiaxing, Zhejiang, 314000, China. Electronic address:

Aims: Shenghua Decoction (SHD) is a well-known classic herbal formula documented in traditional Chinese medicine (TCM) that has been widely applied during the postpartum period in Chinese communities for several years. We conducted this systematic review and meta-analysis to explore the influence of SHD as an adjuvant treatment for early medical abortion using a combination of mifepristone followed by misoprostol.

Methods: This systematic review and meta-analysis was reported using 2020 PRISMA guidelines. Read More

Ann Thorac Surg 2022 Jun 29. Epub 2022 Jun 29.

Department of Cardiovascular Surgery, Mayo Clinic, Rochester, Minnesota.

Background: Left ventricular outflow tract obstruction is common among symptomatic patients with hypertrophic cardiomyopathy (HCM), yet septal reduction by surgical myectomy (SM) is performed infrequently in many centers. We examined the possible relationship between institutional case volume and early outcomes of septal myectomy.

Methods: The Society of Thoracic Surgeons (STS) Adult Cardiac Surgery Database (ACSD) was queried for patients with HCM undergoing septal myectomy from January 2012 to December 2019. Read More

Am Heart J 2022 Jun 29. Epub 2022 Jun 29.

The Zena and Michael A. Wiener Cardiovascular Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA. Electronic address:

Background: ST-segment elevation myocardial infarction (STEMI) is a high-risk patient medical emergency. We developed a secure mobile application, STEMIcathAID, to optimize care for STEMI patients by providing a digital platform for communication between the STEMI care team members, EKG transmission, cardiac catherization laboratory (cath lab) activation and ambulance tracking. The aim of this report is to describe the implementation of the app into the current STEMI workflow in preparation for a pilot project employing the app for inter-hospital STEMI transfer. Read More