Clin Exp Rheumatol 2022 05 29;40(4):863-864. Epub 2022 Apr 29.
Department of Experimental and Clinical Medicine, University of Firenze, and SOD Interdisciplinary Internal Medicine, Behçet Centre and Lupus Clinic, AOU Careggi Hospital of Florence, Italy.
Eur Heart J Case Rep 2022 Aug 2;6(8):ytac294. Epub 2022 Aug 2.
Cardiology Department, Calderdale and Huddersfield NHS Foundation Trust, Halifax, HD3 3EA, UK.
Background: Culture-negative endocarditis is uncommon, occurring in less than a third of all cases of infective endocarditis (IE). Culture-negative IE related to a cardiac device is an even greater diagnostic challenge due to its insidious presentation, with onset of symptoms ranging between 3 and 12 months after device implantation. Sensitivity of the modified Duke's criteria remains low in culture-negative and cardiac device-related IE (CDRIE) since classical signs and symptoms of IE are often absent. Read More
Curr Probl Diagn Radiol 2022 Apr 22. Epub 2022 Apr 22.
Department of Radiodiagnosis and Interventional Radiology, All India Institute of Medical Sciences, New Delhi, India.
Hypersensitivity reactions are characterized by inappropriate response of the immune system to an inciting antigen, which results in damage to various body tissues. Respiratory system can be involved as a part of hypersensitivity reaction by a myriad of conditions ranging from infective pathologies like tuberculosis to non-infective processes such as asthma, graft- versus host disease, sarcoidosis and vasculitic disorders. Recognition of specific imaging features in appropriate clinical setting helps in diagnosing these conditions. Read More
Front Pediatr 2021 13;9:800576. Epub 2021 Dec 13.
Department of Allergology, Rheumatology and Clinical Immunology, Children's Hospital, University Medical Center Ljubljana, Ljubljana, Slovenia.
Necrotizing stomatitis is a rare, acute-onset disease that is usually associated with severely malnourished children or diminished systemic resistance. We describe a 1-year-old girl who developed necrotizing stomatitis, vasculitic rash, skin desquamation on the fingers and toes, and persistent hypertension after serologically confirmed SARS-CoV-2 infection. Her laboratory investigations revealed positive IgG anticardiolipin and IgG anti-β2 glycoprotein antibodies, and biopsy of the mucosa of the lower jaw showed necrosis and endothelial damage with mural thrombi. Read More
Clin Dermatol 2021 Nov-Dec;39(6):966-984. Epub 2021 Jul 25.
Discovery Life Sciences, Powell, Ohio; The Ohio State University Comprehensive Cancer Center, Columbus, Ohio.
A total of 22 patients who had developed an adverse cutaneous reaction to the Moderna or Pfizer vaccine underwent biopsies. Each patient was assessed light microscopically, and, in select biopsies, spike glycoprotein and cytokine assessment were also conducted. The patients developed self-limited cutaneous reactions often described clinically as urticarial or eczematous within 1 day to 4 weeks after receiving the first or second dose of the Pfizer or Moderna vaccine. Read More