Search Our Scientific Publications & Authors

Cell Prolif 2022 Aug 9:e13319. Epub 2022 Aug 9.

Guangdong Provincial Key Laboratory of Large Animal Models for Biomedicine, School of Biotechnology and Health Sciences, Wuyi University, Jiangmen, China.

Objectives: Transplantation of neural progenitor cells (NPCs) derived from human-induced pluripotent stem cells (hiPSCs) is one of the promising treatment strategies for motor neuron diseases (MNDs). However, the inefficiency in committed differentiation of NPCs in vivo limits its application. Here, we tried to establish a potential therapeutic strategy for MNDs by in vivo directional differentiation of hiPSCs engineered with motor neuron (MN) specific transcription factors and Tet-On system. Read More

Radiol Case Rep 2022 Oct 27;17(10):3519-3522. Epub 2022 Jul 27.

Ganesh Shankar Vidyarthi Memorial (G.S.V.M.) Medical College, Kanpur, Uttar Pradesh, India.

Ovarian dermoid cysts, also known as mature teratomas, are benign embryonal tumors with a slow growth rate. They are the consequence of ectodermal components becoming trapped along with their closure sites and account for the most common germinative ovarian tumor in reproductive-aged women. These patients may have a reduced risk of morbidity if they receive an accurate diagnosis and extensive follow-up care. Read More

Front Genet 2022 14;13:936292. Epub 2022 Jul 14.

Institute of Genetics, School of Basic Medical Sciences, Lanzhou University, Lanzhou, China.

Hereditary Spastic Paraplegia (HSP) is considered to be one of the common neurodegenerative diseases with marked genetic heterogeneity. Recently, the mutations in ubiquitin-associated protein 1 () have been described in patients with HSP, known as spastic paraplegias 80 (SPG80). Here, we reported a Chinese HSP family presenting a frameshift mutation in the gene leading to complex HSP. Read More

Zhonghua Bing Li Xue Za Zhi 2022 Aug;51(8):779-781

Department of Pathology, Gansu Maternity and Child Health Care Hospital, Lanzhou 730050, China.

Ghana Med J 2022 Mar;56(1):46-50

Department of Surgery, Korle Bu Teaching Hospital, Accra, Ghana.

A tailgut cyst is a rare congenital lesion that develops from a residual posterior remnant of the intestine and presents as a mass in the presacral space. They are generally asymptomatic or have atypical symptoms, are usually benign but may rarely become malignant. We report a case of a 37-year-old female who initially presented to the Surgical Department of Korle Bu Teaching Hospital, Accra, Ghana with a malignant tailgut cyst after having repeated surgical procedures for recurrent perianal infective pathologies but still had persistence of symptoms. Read More