Search Our Scientific Publications & Authors

Neurology 2022 Aug;99(7 Supplement 1):42-51

From the Department of Neurology (J.M.J.D., S.S., E.R., S.K.L.D., B.R.B.), Radboud University Medical Center, Donders Institute for Brain, Cognition and Behavior; Center of Expertise for Parkinson & Movement Disorders (J.M.J.D., S.S., S.K.L.D., B.R.B.); and Radboud University Medical Center Alzheimer Center (E.R.), the Netherlands.

The prevalence of Parkinson disease (PD) is growing fast, amplifying the quest for disease-modifying therapies in early disease phases where pathology is still limited. Lifestyle interventions offer a promising avenue for preventing progression from prodromal to manifest PD. We illustrate this primarily for 1 specific lifestyle intervention, namely aerobic exercise because the case for the other main lifestyle factor (dietary interventions) to modify the course of prodromal PD is currently less persuasive. Read More

Environ Pollut 2022 Aug 12:119924. Epub 2022 Aug 12.

The International Peace Maternity and Child Health Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, 200030, China; Shanghai Key Laboratory of Embryo Original Diseases, Shanghai, 200030, China; Institute of Birth Defects and Rare Diseases, School of Medicine, Shanghai Jiao Tong University, Shanghai, 200030, China. Electronic address:

Nanoplastics (NPs), the emerging contaminants in recent years, widely distributed in the environment and are bioaccumulated and biomagnified in organisms through food chain. A growing number of studies have detected plastic particulates in human placenta and blood. However, few studies have focused on their effects during human pregnancy. Read More

J Allergy Clin Immunol 2022 Aug 12. Epub 2022 Aug 12.

Division of Allergy and Immunology, Northwestern University Feinberg School of Medicine, Chicago, IL.

Background: Chronic rhinosinusitis with nasal polyposis is associated with a significant disease burden. The optimal use and administration route for intranasal corticosteroids (INCS) when managing CRSwNP are unclear.

Objective: To systematically synthesize the evidence addressing INCS for CRSwNP. Read More

Am J Trop Med Hyg 2022 Aug 15. Epub 2022 Aug 15.

Section of Infectious Diseases, Department of Medicine, Boston Medical Center and Boston University School of Medicine, Boston, Massachusetts.

Mycobacterium tuberculosis (Mtb) is a complex pathogen causing multiple possible disease states in its host including latency, active disease, and elimination. While there is reasonable indirect evidence of elimination of tuberculosis (TB) in the absence of treatment, direct reports of autoregression are rare. We report a case of smear-negative, polymerase chain reaction (PCR)-positive TB disease regression in the absence of therapy due to severe adverse effects from antimycobacterial drugs. Read More

Food Chem Toxicol 2022 Aug 12:113365. Epub 2022 Aug 12.

Division of Pathology, National Institute of Health Sciences, Kanagawa, Japan; Yamazaki University of Animal Health, Technology, Tokyo, Japan. Electronic address:

2-Methylfuran (2-MF) exists naturally in foods and is used as a flavoring agent. Furan, the core structure of 2-MF, possesses hepatocarcinogenicity in rodents. Accumulation of toxicological information on furan derivatives is needed to elucidate their carcinogenic mode of action. Read More