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Social cognitive outcomes are associated with improvements in mobility performance following lifestyle intervention in prostate cancer patients undergoing androgen deprivation therapy.

Authors:
Zachary L Chaplow Alexander R Lucas Elizabeth Grainger Christina Simpson Ciaran M Fairman Victoria R DeScenza Jessica Bowman Steven K Clinton Brian C Focht

PLoS One 2022 27;17(1):e0263136. Epub 2022 Jan 27.

Kinesiology, Department of Human Sciences, The Ohio State University, Columbus, Ohio, United States of America.

Objective: To compare the effects of an exercise and dietary intervention with those of standard-of-care management upon change in lift and carry performance and mobility-related self-efficacy beliefs and explore associations in prostate cancer patients undergoing androgen deprivation therapy.

Methods: 32 prostate cancer patients (M age = 66.2 years; SD = 7.8) undergoing androgen deprivation therapy were randomly assigned to a 3-month exercise and dietary lifestyle intervention (n = 16) or standard-of-care management (n = 16). Outcome assessments were obtained at baseline, 2- and 3-month follow-up.

Results: The lifestyle intervention resulted in significantly greater improvements in lift and carry performance (p = 0.01) at 2 Months (d = 1.01; p < 0.01) and 3 Months (d = 0.95; p < 0.01) and superior improvements in mobility-related self-efficacy at 2 Months (d = 0.38) and 3 Months (d = 0.58) relative to standard-of-care. Mobility-related self-efficacy (r = -.66; p = 0.006) and satisfaction with function (r = -.63; p = 0.01) were significantly correlated with lift and carry performance at 3 Months.

Conclusions: The exercise and dietary lifestyle intervention yielded superior improvements in lift and carry performance and mobility-related self-efficacy relative to standard-of-care and key social cognitive outcomes were associated with more favorable mobility performance.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0263136PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8794107PMC
February 2022

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