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Int J Biol Macromol 2022 May 18;212:31-42. Epub 2022 May 18.

Jiangxi Key Laboratory of Natural Product and Functional Food, College of Food Science and Engineering, Jiangxi Agricultural University, Nanchang 330045, China. Electronic address:

The study was aimed to investigate the effect of Cyclocarya paliurus polysaccharides (CPP) and the sulfation derivative (S-CPP) on modulate intestinal mucosal immunity and intestinal microbiota in cyclophosphamide-induced mice. The results showed that CPP and S-CPP effectively alleviated intestinal villi injury, enhanced the contents of interleukin-1β (IL-1β) and tumor necrosis factor-α (TNF-α) in small intestinal tissue and serum, and upregulated IL-1β at gene levels, zonula occludens-1 (ZO-1), Occludin and Claudin-1 at gene and protein levels, thereby promoting the repair of intestinal mechanical barrier and enhancing intestinal mucosal immunity. Moreover, the beneficial modulation of CPP and S-CPP on the overall structure of intestinal microbiota was revealed by performing 16S ribosomal RNA (16S rRNA) sequencing. Read More

Ecotoxicol Environ Saf 2022 May 18;239:113641. Epub 2022 May 18.

Department of Biological Science and Technology, Nanjing University, Nanjing 210093, PR China. Electronic address:

The effluent of wastewater treatment plants (WWTPs) is an important water resource for some rivers in regions with relatively low precipitation, which may pose ecological risks. Various pollutants and microorganisms are discharged into rivers, along with the WWTP effluent, but this process has not been thoroughly studied. The objective of this study was to evaluate the effect of WWTP effluent on the bacterial community in the sediment and water column of an urban river and to identify the relationship between the total and active bacterial communities. Read More

BMC Cancer 2022 May 20;22(1):566. Epub 2022 May 20.

Department of Integrated Chinese and Western Medicine, Institute of Basic Medicine and Cancer (IBMC), The Cancer Hospital of the University of Chinese Academy of Sciences (Zhejiang Cancer Hospital), Chinese Academy of Sciences, 310022, Hangzhou, Zhejiang, China.

Background: The role of Berberine (BBR) in colorectal cancer (CRC) and gut microbiota has begun to appreciate. However, there was no direct evidence confirm that the gut microbiota regulated by BBR could inhibit CRC. This report investigated the effect of stool from BBR treated subjects and its effect on CRC. Read More

J Psychosom Res 2022 May 13;158:110942. Epub 2022 May 13.

LWL University Hospital, Department of Psychiatry, Psychotherapy and Preventive Medicine, Division of Social Neuropsychiatry and Evolutionary Medicine, Ruhr University Bochum, Germany. Electronic address:

Objective: A growing body of research has shown that people with a wide range of psychiatric disorders, including depression, present with alterations of the gut microbiota, although it is unclear if differences may be caused by the action of psychotropic medication. No data exist for patients with borderline personality disorder (BPD), a psychiatric condition that is frequently comorbidly associated with depression.

Methods: Twenty-four unmedicated patients and twenty-one age- and sex-matched healthy controls were recruited. Read More

Infect Drug Resist 2022 12;15:2475-2480. Epub 2022 May 12.

Department of Clinical Laboratory, First Affiliated Hospital of Anhui Medical University, Hefei, People's Republic of China.

Background: is an environmental saprophyte that potentially causes various infections in humans. It has been reported to cause rare opportunistic infections in immunocompromised patients or patients with indwelling foreign bodies.

Case Presentation: We report a case of continuous ambulatory peritoneal dialysis (CAPD)-related peritonitis caused by (). Read More