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Macromol Biosci 2022 May 21:e2200029. Epub 2022 May 21.

Innovation Center for Textile Science and Technology, Donghua University, Shanghai, 201620, China.

Paracetamol is a safe and widely used antipyretic and analgesic drug, however, with the drawbacks of gastrointestinal first-pass effect and short intervals of administration. Transdermal drug delivery system can effectively avoid the liver metabolism caused by excess oral ingestion of Paracetamol. Herein, we propose a silk fabric-based medical dressing decorated by a thermo-responsive hydrogel for sustained release of paracetamol. Read More

Biophys J 2022 May 20. Epub 2022 May 20.

Department of Mechanical and Aerospace of Engineering, University of Central Florida, 4000 Central Florida Blvd., Orlando, FL 32816, USA. Electronic address:

The newly developed finite element modeling at the atomic scale was used to predict the static and dynamic response of the alpha-helix (AH) and tropocollagen (TC) protein fragments, the main building blocks of the spike of the SARS-CoV-2. The geometry and morphology of the spike's stalk and its connection to the viral envelope were determined from the combination of most recent Molecular Dynamics simulation and images of Cryo-Electron microscope. The stiffness parameters of the covalent bonds in the main chain of the helix were taken from the literature. Read More

Biophys J 2022 May 20. Epub 2022 May 20.

Carnegie Mellon University, Department of Physics, Pittsburgh, PA 15213, USA.

Actin is one of the key structural components of the eukaryotic cytoskeleton that regulates cellular architecture and mechanical properties. Dynamic regulation of actin filament length and organization is essential for the control of many physiological processes including cell adhesion, motility and division. While previous studies have mostly focused on the mechanisms controlling the mean length of individual actin filaments, it remains poorly understood how distinct actin filament populations in cells maintain different lengths using the same set of molecular building blocks. Read More

Bioresour Technol 2022 May 18:127316. Epub 2022 May 18.

School of Environmental & Safety Engineering, Liaoning Petrochemical University, Fushun 113001, China. Electronic address:

This study successfully prepared a novel sulfur-doped nano zero-valent iron @biochar ([email protected]) by modifying corn stover biochar with Fe and S using a mechanical ball milling method for effective phosphorus (P) adsorption in the waterbody. Batch experiments revealed that [email protected] (BC/S/Fe=3:1:1) reached a Q of 25.00 mg P/g and followed PFO and Langmuir models. Read More

Chemosphere 2022 May 18;303(Pt 1):134997. Epub 2022 May 18.

Department of Mechanical Engineering, St.Peter's Institute of Higher Education and Research, Chennai, Tamil Nadu, India.

Occupancy of waste micro plastic particles in the beach sand is found hazardous sea livings as well as creates the environmental issues. Many research attempts have been made to short out them. This investigation focuses on utilizing such micro plastic to produce cost effective ABS plasticproducts including toys manufacturing. Read More