Pubfacts - Scientific Publication Data
  • Categories
  • |
  • Journals
  • |
  • Authors
  • Login
  • Categories
  • Journals

Search Our Scientific Publications & Authors

Publications
  • Publications
  • Authors
find publications by category +
Translate page:

The effect of COVID-19 lockdown on the glycemic control of children with type 1 diabetes.

Authors:
Elina Hakonen Tero Varimo Anna-Kaisa Tuomaala Päivi J Miettinen Mari-Anne Pulkkinen

BMC Pediatr 2022 01 19;22(1):48. Epub 2022 Jan 19.

Pediatric Research Center, New Children's Hospital, Helsinki University Hospital, Stenbäckinkatu 9, HUS 00029, PO Box 347, Helsinki, Finland.

Background: Between March 18 and May 13 2020, the COVID-19 pandemic outbreak in Finland resulted in the closure of schools and the limitation of daycare (i.e. lockdown). Social distancing changed the daily routines of children with type 1 diabetes (T1D). Healthcare professionals were forced to adapt to the pandemic by replacing physical outpatient visits with virtual visits. However, the influence of the lockdown on glycemic control in these patients remained unknown.

Methods: In this retrospective register study from a pediatric diabetes outpatient clinic, we analyzed the glycemic data of T1D patients (n = 245; aged 4 to 16 years) before and under the lockdown. All the participants used continuous glucose monitoring (rtCGM or iCGM), two-thirds were on insulin pumps (CSII), and one-third on multiple daily insulin injections (MDI) therapy.

Results: In our patient cohort, time in range (TIR, n = 209) and mean glucose levels (n = 214) were similar prior to and under the lockdown (mean change 0.44% [95%CI: -1.1-2.0], p = 0.56 and -0.13 mmol/mol [95%CI: -0.3-0.1], p = 0.17, respectively). However, children treated with CSII improved their glycemic control significantly during the lockdown: TIR improved on average 2.4% [0.6-4.2] (p = 0.010) and mean blood glucose level decreased -0.3 mmol/mol [-0.6-(-0.1)] (p = 0.008). The difference was more pronounced in girls, adolescents and patients using conventional insulin pumps.

Conclusions: The glycemic control in T1D children did not deteriorate under the lockdown, and patients on CSII even improved their control, which suggests that social distancing might have allowed families to use the insulin pump more accurately as out-of-home activities were on hold.

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12887-022-03115-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8766349PMC
January 2022

Publication Analysis

Top Keywords

glycemic control
16
csii improved
8
lockdown glycemic
8
children type
8
type diabetes
8
social distancing
8
lockdown
6
glycemic
5
control
5
n = 214 prior
4
time range
4
range tir
4
tir n = 209
4
n = 209 glucose
4
glucose levels
4
levels n = 214
4
044% [95%ci
4
prior lockdown
4
lockdown change
4
change 044%
4

Keyword Occurance

Similar Publications

Review of present method of glucose from human blood and body fluids assessment.

Authors:
Klara Fiedorova Martin Augustynek Jan Kubicek Petr Kudrna Daniele Bibbo

Biosens Bioelectron 2022 May 13;211:114348. Epub 2022 May 13.

Department of Industrial, Electronic and Mechanical Engineering, University of Roma Tre, Via Vito Volterra, 62, 00146, Rome, Italy. Electronic address:

the work has been aimed to create an overview of available and used methods and ways to determine the concentration of glucose in body fluids, especially from a technical point of view. It also provides an overview of the clinical features of these methods. The survey found that today's market offers a large number of options and approaches to the issue. Read More

View Article and Full-Text PDF
May 2022
Similar Publications

Whey protein supplementation improves postprandial glycemia in persons with type 2 diabetes mellitus: A systematic review and meta-analysis of randomized controlled trials.

Authors:
Shih-Wen Chiang Han-Wen Liu El-Wui Loh Ka-Wai Tam Jzy-Yu Wang Wei-Lin Huang Yi-Chun Kuan

Nutr Res 2022 Apr 18;104:44-54. Epub 2022 Apr 18.

Cochrane Taiwan, Taipei Medical University, Taipei, 110301, Taiwan; Center for Evidence-Based Health Care, Department of Medical Research, Taipei Medical University-Shuang Ho Hospital, New Taipei City, 235041, Taiwan; Taipei Neuroscience Institute, Taipei Medical University, Taipei, 110301, Taiwan; Department of Neurology, Taipei Medical University-Shuang Ho Hospital, New Taipei City, 235041, Taiwan; Department of Neurology, School of Medicine, College of Medicine, Taipei Medical University, Taipei, 110301, Taiwan; Institute of Epidemiology and Preventive Medicine, College of Public Health, National Taiwan University, Taipei, 100025, Taiwan. Electronic address:

Whey protein (WP) can increase insulin secretion, produce an incretin effect, delay gastric emptying, and regulate appetite, resulting in improved glycemic control. We hypothesized that WP supplementation is associated with postprandial glycemia regulation in persons with type 2 diabetes mellitus (T2DM) and conducted a quantitative meta-analysis of randomized controlled trials (RCTs) to test this hypothesis. We searched PubMed, Embase, Cochrane Library, Scopus databases, and the ClinicalTrials. Read More

View Article and Full-Text PDF
April 2022
Similar Publications

Development of a pharmacist-managed protocol for the transition from intravenous to subcutaneous insulin in critically ill adults.

Authors:
Jenna M Gerhardt Serena A Dine David R Foster Andrew C Lodolo Allyson M McIntire Michael J Peters Taylor A Rhew Todd A Walroth

Am J Health Syst Pharm 2022 May 23. Epub 2022 May 23.

Eskenazi Health, Indianapolis, IN, USA.

Disclaimer: In an effort to expedite the publication of articles related to the COVID-19 pandemic, AJHP is posting these manuscripts online as soon as possible after acceptance. Accepted manuscripts have been peer-reviewed and copyedited, but are posted online before technical formatting and author proofing. These manuscripts are not the final version of record and will be replaced with the final article (formatted per AJHP style and proofed by the authors) at a later time. Read More

View Article and Full-Text PDF
May 2022
Similar Publications

Maternal Body Mass Index, Diabetes, and Gestational Weight Gain and Risk for Pediatric Cancer in Offspring: A Systematic Review and Meta-Analysis.

Authors:
Andrew R Marley Allison Domingues Taumoha Ghosh Lucie M Turcotte Logan G Spector

JNCI Cancer Spectr 2022 Mar;6(2)

Division of Epidemiology & Clinical Research, Department of Pediatrics, University of Minnesota, Minneapolis, MN, USA.

Background: Pediatric cancer incidence has steadily increased concurrent with rising adult obesity, but associations between maternal obesity and associated comorbidities and pediatric cancer risk remain understudied. We aimed to quantitatively characterize associations of pediatric cancer risk with maternal prepregnancy body mass index (BMI), gestational weight gain, and maternal diabetes.

Methods: We performed a comprehensive and systematic literature search in Ovid and EMBASE from their inception to March 15, 2021. Read More

View Article and Full-Text PDF
March 2022
Similar Publications

Local Dexamethasone Administration Delays Allogeneic Islet Graft Rejection in the Anterior Chamber of the Eye of Non-Human Primates.

Authors:
Sai Bo Bo Tun Minni Chua Gavin Siew Wei Tan Ingo Leibiger Yusuf Ali Veluchamy Amutha Barathi Per-Olof Berggren

Cell Transplant 2022 Jan-Dec;31:9636897221098038

Translational Pre-Clinical Model Platform, Singapore Eye Research Institute, Singapore.

Pancreatic islet transplantation into the anterior chamber of the eye (ACE) has been shown to improve glycemic control and metabolic parameters of diabetes in both murine and primate models. This novel transplantation site also allows the delivery of therapeutic agents, such as immunosuppressive drugs, locally to prevent islet graft rejection and circumvent unwanted systemic side effects. Local intravitreal administration of micronized dexamethasone implant was performed prior to allogeneic islet transplantation into the ACEs of non-human primates. Read More

View Article and Full-Text PDF
May 2022
Similar Publications
}
© 2022 PubFacts.
  • About PubFacts
  • Privacy Policy
  • Sitemap