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BMJ Case Rep 2022 May 23;15(5). Epub 2022 May 23.

Programa de Salud Sexual y Reproductiva, Partners In Health México/Compañeros En Salud, Ángel Albino Corzo, Chiapas, México.

Globally, obstetric emergencies majorly account for maternal morbidity and mortality. Guerrero, Oaxaca and Chiapas accounted for more than 13% of maternal deaths in the country in 2021. Obstetric haemorrhage was the leading cause of maternal death after COVID-19 infection and hypertensive disorders. Read More

Sci Total Environ 2022 May 20:156146. Epub 2022 May 20.

School of Public Health, Anhui Medical University, No. 81 Meishan Road, Hefei 230032, Anhui, China; Key Laboratory of Population Health Across Life Cycle, Anhui Medical University, Ministry of Education of the People's Republic of China, No. 81 Meishan Road, Hefei 230032, Anhui, China; NHC Key Laboratory of Study on Abnormal Gametes and Reproductive Tract, Anhui Medical University, No. 81 Meishan Road, Hefei 230032, Anhui, China; Anhui Provincial Key Laboratory of Population Health and Aristogenics, Anhui Medical University, No. 81 Meishan Road, Hefei 230032, Anhui, China. Electronic address:

Background: Studies on potential maternal thyrotoxicity related to tetracycline antibiotics exposure during pregnancy are lacking. Based on a large prospective cohort study, this study aimed to examine the associations between tetracycline antibiotics exposure in maternal urine and maternal thyroid hormone parameters.

Methods: Based on the Ma'anshan Birth Cohort study, urine and serum samples of 2969 pregnant women were collected in the first, second and third trimesters. Read More

Clin Microbiol Infect 2022 May 20. Epub 2022 May 20.

Department of Pediatric Intensive Care Unit, Necker Enfants Malades Hospital, Université de Paris, AP-HP, France; Pharmacology and Drug Evaluation in Children and Pregnant Women EA7323, Université de Paris, France.

Objective: Cefepime is commonly used in pediatric intensive care units (PICUs), where unpredictable variations in the patients' pharmacokinetic (PK) variables may require drug dose adjustments. The objectives of the present study were to build a population PK model for cefepime in critically ill children and to optimize individual initial dosing regimens.

Methods: Children (aged from 1 month to 18 years; bodyweight >3 kg) receiving cefepime were included. Read More

J Affect Disord 2022 May 20. Epub 2022 May 20.

Department of Psychology, Sapienza University, Rome, Italy. Electronic address:

Background: During pregnancy women experience rapid and unique changes in body weight, shape and size over a relatively short time period. While research focused on the role of external bodily modifications during pregnancy, research on internal bodily variations is missing.

Methods: In a longitudinal study, we recruited healthy pregnant women and measured whether and how depressive symptoms, body image dissatisfaction and the subjective tendency to focus on one's own internal bodily sensations, i. Read More

Gynecol Obstet Invest 2022 May 23:1-9. Epub 2022 May 23.

Department of Obstetrics and Gynecology, Qinghai Red-Cross Hospital, Xining, China.

Objectives: Fetal macrosomia and its associated complications are the most frequent and serious morbidities for infants associated with gestational diabetes mellitus (GDM). In this study, we aimed to determine the expression of circulating circRNAs in humans, which may be promising biomarkers for the diagnosis of GDM or predicting the macrosomia in GDM patients.

Design: A multi-stage validation and risk score formula analysis was applied for validation. Read More