The development of efficient bifunctional catalysts for both hydrogen evolution reaction (HER) and oxygen evolution reaction (OER) is essential for reducing the cost of hydrogen production by water splitting. Herein, hollow microtubes composed of RuNiCo alloy nanoparticles uniformly embedded in the carbon matrix (RuNiCo@CMT) are prepared through a simple impregnation followed by reduction. Benefiting from the unique mosaic structure and the synergistic effect between Ru and NiCo, RuNiCo@CMT achieves more exposed active sites and improved reaction kinetics.