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BMJ Case Rep 2022 May 24;15(5). Epub 2022 May 24.

Respiratory Medicine, Guy's and St Thomas' Hospitals NHS Trust, London, UK.

A healthy, immunocompetent South Asian man in his mid-20s, with a medical history of gastric ulcer, presented to Accident & Emergency with pleuritic chest pain, shortness of breath, fever, night sweats, weight loss, dry cough and asymptomatic iron deficiency anaemia. Following his initial assessment and investigations (chest X-ray, CT and blood tests), a diagnosis of miliary tuberculosis (TB) was made and empirical antimicrobial treatment started. However, subsequent microbiological testing, including urine, blood, induced sputum and lymph node sampling, was negative. Read More

Epidemiol Health 2022 May 16:e2022047. Epub 2022 May 16.

Division of Nutrition, Department of Pediatrics, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.

Objectives: Malnutrition in hospitalized patients is a frequently overlooked health issue. We aimed to assess the prevalence and pattern of nutritional disorders in hospitalized Thai children from a National Health database.

Methods: Hospitalized children aged 1 month-18 years diagnosed with nutritional disorders between 2015 and 2019 were retrospectively reviewed using the National Health Security Office data. Read More

J Nutr Biochem 2022 May 21:109065. Epub 2022 May 21.

Department of Nutrition and Integrative Physiology, Florida State University, Tallahassee, FL, USA. Electronic address:

Enteric infections are widespread in infants and children living in low-resource settings. Iron availability in the gastrointestinal tract may modify the gut microbiome and impact the incidence and severity of enteropathy. This study was designed to determine the effect of an iron-deplete compared to an iron-rich environment in the lower intestine on the gut microbiome, and whether iron availability in the lower intestine affects the host immune response and severity of enteric infection in young mice. Read More

Chest 2022 May 21. Epub 2022 May 21.

Massachusetts General Hospital Sleep Disorders Clinical Research Program, One Bowdoin Square, 10(th) Floor, Boston, MA, 02114.

RLS is a sensory-motor neurological disorder, present to a clinically significant degree in 2-3% of the adult population, more commonly with advancing age and in women, which dramatically affects sleep and quality of life. Addressing factors that worsen RLS (iron deficiency, antidepressant or antihistamine administration, obstructive sleep apnea) is an important first step in treatment. RLS can generally be well treated with medications such as alpha-2-delta calcium channel ligands (A2Ds) gabapentin, pregabalin, gabapentin enacarbil or, if these are poorly tolerated or lack efficacy, dopamine agonists (DAs), pramipexole, ropinirole or rotigotine. Read More

Cureus 2022 Apr 21;14(4):e24330. Epub 2022 Apr 21.

2nd Department of Internal Medicine, General and Oncology Hospital of Kifissia "Agioi Anargyroi", Athens, GRC.

Although hemoglobin levels beneath 6.5 g/dl are considered to be life-threatening and the patients theoretically suffer from a cluster of symptoms, few cases of patients who seek medical assistance when their hemoglobin levels had fallen beneath 3 g/dl have been reported in the literature. Here, we describe the case of a 97-year-old patient who was transferred to the emergency department with dyspnea and the initial screening tests showed a hemoglobin level of 1. Read More