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Int Arch Allergy Immunol 2022 16;183(5):490-497. Epub 2021 Dec 16.

Department of Clinical Immunology, School of Medical Laboratory, Tianjin Medical University, Tianjin, China.

Background: Light-initiated chemiluminescence assay (LICA) is a homogeneous assay that has been successfully used for the quantitation of food allergen-specific immunoglobulin E (sIgE), but not inhaled allergen-sIgE. Simultaneously, current assays used to detect allergen-sIgE are serum consuming and/or time consuming. Hence, we established a method for the quantitation of Artemisia-sIgE based on LICA and verified its performance according to the clinical guideline documents, laying a foundation for the quantitation of inhaled and food allergen-sIgE in parallel on LICA. Read More

Phys Rev Lett 2020 Nov;125(19):192501

Department of Physics and Astronomy, Aarhus University, DK-8000 Aarhus, Denmark.

The β decay of ^{208}Hg into the one-proton hole, one neutron-particle _{81}^{208}Tl_{127} nucleus was investigated at CERN-ISOLDE. Shell-model calculations describe well the level scheme deduced, validating the proton-neutron interactions used, with implications for the whole of the N>126, Z<82 quadrant of neutron-rich nuclei. While both negative and positive parity states with spin 0 and 1 are expected within the Q_{β} window, only three negative parity states are populated directly in the β decay. Read More

ACS Infect Dis 2020 01 6;6(1):3-13. Epub 2019 Dec 6.

Global Health Institute of Merck, Ares Trading S.A. , a subsidiary of Merck KGaA Darmstadt Germany , Route de Crassier 1 , 1262 Eysins , Switzerland.

In May 2019, the Wellcome Centre for Anti-Infectives Research (CAIR) at the University of Dundee, UK, held an international conference with the aim of discussing some key questions around discovering new medicines for infectious diseases and a particular focus on diseases affecting Low and Middle Income Countries. There is an urgent need for new drugs to treat most infectious diseases. We were keen to see if there were lessons that we could learn across different disease areas and between the preclinical and clinical phases with the aim of exploring how we can improve and speed up the drug discovery, translational, and clinical development processes. Read More

Disabil Rehabil Assist Technol 2016 13;11(5):413-22. Epub 2014 Nov 13.

c School of Health Sciences & Social Care , Brunel University , London , UK.

Purpose: This paper proposes a novel system (using the Nintendo Wii remote) that offers customised, non-immersive, virtual reality-based, upper-limb stroke rehabilitation and reports on promising preliminary findings with stroke survivors.

Method: The system novelty lies in the high accuracy of the full kinematic tracking of the upper limb movement in real-time, offering strong personal connection between the stroke survivor and a virtual character when executing therapist prescribed adjustable exercises/games. It allows the therapist to monitor patient performance and to individually calibrate the system in terms of range of movement, speed and duration. Read More