Am J Transplant 2021 Nov 27. Epub 2021 Nov 27.
Center for Gut Rehabilitation and Transplantation, Department of General Surgery, Digestive Disease and Surgery Institute, Cleveland Clinic, Cleveland, Ohio.
Curr Opin Pediatr 2022 Jan 19. Epub 2022 Jan 19.
Department of Pediatrics, University of South Florida Morsani College of Medicine, Tampa, Florida, USA.
Purpose Of Review: Parenteral nutrition is an integral part of the care of infants in the neonatal ICU. However, prolonged use of parenteral nutrition can be associated with adverse outcomes, most notably parenteral nutrition-associated liver disease, now known as intestinal failure-associated liver disease (IFALD). This review highlights pertinent developments in the epidemiology of IFALD as it pertains to neonates and showcases recent advances in the pathophysiology, treatment, and outcomes of neonates with IFALD. Read More
J Exp Med 2022 Mar 20;219(3). Epub 2022 Jan 20.
Wihuri Research Institute, Biomedicum Helsinki, Helsinki, Finland.
Vascular endothelial growth factors (VEGFs) and their receptors (VEGFRs) are quintessential for the development and maintenance of blood and lymphatic vessels. However, genetic interactions between the VEGFRs are poorly understood. VEGFR2 is the dominant receptor that is required for the growth and survival of the endothelium, whereas deletion of VEGFR1 or VEGFR3 was reported to induce vasculature overgrowth. Read More
Metabolites 2022 Jan 5;12(1). Epub 2022 Jan 5.
Global Obesity and Liver Disease Research, Global Drug Discovery, Novo Nordisk A/S, Novo Park 1, 2670 Måløv, Denmark.
Obesity is caused by prolonged energy surplus. Current anti-obesity medications are mostly centralized around the energy input part of the energy balance equation by increasing satiety and reducing appetite. Our gastrointestinal tract is a key organ for regulation of food intake and supplies a tremendous number of circulating signals that modulate the activity of appetite-regulating areas of the brain by either direct interaction or through the vagus nerve. Read More
Animals (Basel) 2022 Jan 12;12(2). Epub 2022 Jan 12.
Agro-Technological Institute of Castilla y León, Ctra. Arévalo s/n, 40196 Segovia, Spain.
The demand of optimal protein for human consumption is growing. The Food and Agriculture Organization (FAO) has highlighted aquaculture as one of the most promising alternatives for this protein supply gap due to the high efficiency of fish growth. However, aquaculture has been facing its own sustainability problem, because its high demand for protein has been traditionally satisfied with the use of fishmeal (FM) as the main source. Read More
Animals (Basel) 2022 Jan 11;12(2). Epub 2022 Jan 11.
Centro de Enseñanza, Investigación y Extensión en Producción Avícola CEIEPAv, Tláhuac 13300, Mexico.
This study was conducted to evaluate the productive performance, intestinal health, and description of the cecum microbiota in broilers supplemented with β-mannanases (MNs) and bacteriophages (BPs). Six hundred one-day-old broilers were divided into four groups and fed one of the following diets: CON-corn-soybean meal + 10 ppm enramycin (ENR); MN: CON + 500 ppm MN; BP: CON + 500 ppm BP; MN + BP: BP + 500 ppm MN. The BP and MN factors showed similar performances to ENR. Read More