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Harmful Algae 2022 Jun 30;115:102231. Epub 2022 Mar 30.

Laboratoire des Sciences de l'Environnement Marin, UMR 6539 CNRS/UBO - Institut Universitaire Européen de la Mer, Technopôle Brest-Iroise, 29280 Plouzané, France.

The king scallop, Pecten maximus is a highly valuable seafood in Europe. Over the last few years, its culture has been threatened by toxic microalgae during harmful algal blooms, inducing public health concerns. Indeed, phycotoxins accumulated in bivalves can be harmful for human, especially paralytic shellfish toxins (PST) synthesized by the microalgae Alexandrium minutum. Read More

Biophys J 2022 May 25. Epub 2022 May 25.

Department of Chemical and Biomolecular engineering, University of Pennsylvania, Philadelphia, PA, 19104, USA; Department of Bioengineering, University of Pennsylvania, Philadelphia, PA, 19104, USA. Electronic address:

The plasma membrane hosts a wide range of biomolecules, mainly proteins and carbohydrates, that mediate cellular interactions with its environment. The crowding of such biomolecules regulates cellular morphologies and cellular trafficking. Recent discoveries have shown that the structure and density of cell surface polymers and hence the signaling machinery change with the state of the cell, especially in cancer progression. Read More

Transl Res 2022 May 21. Epub 2022 May 21.

Department of Cardiology, the First Affiliated Hospital, Harbin Medical University, Harbin, 150001, China; NHC Key Laboratory of Cell Translation, Harbin Medical University, Heilongjiang, 150001, China; Key Laboratory of Cardiac Diseases and Heart Failure, Harbin Medical University, Harbin, 150001, China; Key Laboratory of Hepatosplenic Surgery, Harbin Medical University, Ministry of Education, Harbin, 150001, China. Electronic address:

Cardiac fibrosis is a process characterized by extracellular matrix accumulation leading to myocardial dysfunction. Angiotensin II (Ang II) has been shown to play an important role in the pathogenesis of cardiac fibrosis. However, the underlying mechanisms are not well established. Read More

Front Plant Sci 2022 6;13:784342. Epub 2022 May 6.

Department of Molecular Genetics, The Ohio State University, Columbus, OH, United States.

The linker of nucleoskeleton and cytoskeleton (LINC) complex is a protein complex spanning the inner and outer membranes of the nuclear envelope. Outer nuclear membrane KASH proteins interact in the nuclear envelope lumen with inner nuclear membrane SUN proteins. The paralogous Arabidopsis KASH proteins SINE1 and SINE2 function during stomatal dynamics induced by light-dark transitions and ABA. Read More

Clin Proteomics 2022 May 19;19(1):15. Epub 2022 May 19.

Institute for Clinical and Translational Research (ICTR), University of Wisconsin-Madison, 715 Highland Ave, Madison, WI, 53705, USA.

Background: Airway remodeling in patients with asthma, which leads to a decline in pulmonary function, is likely the result of repeated exacerbations often provoked by aeroallergen exposures. Aeroallegen exposure triggers a stereotypic response orchestrated by growth factor cytokines and other protein mediators. This results in a late-phase allergic reaction characterized by vascular permeability, recruitment of activated leukocytes, and activation of structural cells of the airway. Read More