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Eur Phys J E Soft Matter 2022 May 23;45(5):50. Epub 2022 May 23.

Dipartimento di Biotecnologie Mediche e Medicina Traslazionale, Universitá degli Studi di Milano, 20090, Segrate, Italy.

The connection between the properties of a cell tissue and those of the single constituent cells remains to be elucidated. At the purely mechanical level, the degree of rigidity of different cellular components, such as the nucleus and the cytoplasm, modulates the interplay between the cell inner processes and the external environment, while simultaneously mediating the mechanical interactions between neighboring cells. Being able to quantify the correlation between single-cell and tissue properties would improve our mechanobiological understanding of cell tissues. Read More

Endokrynol Pol 2022 ;73(2):336-345

Department of Burns and Plastic Surgery, the First Affiliated Hospital of Hunan University of Chinese Medicine, Changsha, Hunan, China.

Introduction: The high glucose changes caused by diabetes mellitus (DM) can damage the vascular system. Astragaloside IV (AS-IV) can improve diabetes and promote angiogenesis. Exosomes (EXOs) help to carry specific drugs into cells efficiently. Read More

Front Cell Dev Biol 2022 3;10:883491. Epub 2022 May 3.

Department of Cell Biology, National Institute for Basic Biology, Okazaki, Japan.

Peroxisomes are present in eukaryotic cells and have essential roles in various biological processes. Plant peroxisomes proliferate by biosynthesis or division of pre-existing peroxisomes, degrade, or replace metabolic enzymes, in response to developmental stages, environmental changes, or external stimuli. Defects of peroxisome functions and biogenesis alter a variety of biological processes and cause aberrant plant growth. Read More

Parasit Vectors 2022 May 17;15(1):170. Epub 2022 May 17.

Key Laboratory of Zoonosis Research of the Ministry of Education, The Institute of Zoonosis, The College of Veterinary Medicine, Jilin University, Changchun, 130062, China.

Background: Cryptosporidium parvum is a zoonotic parasite and member of the phylum Apicomplexa with unique secretory organelles, including a rhoptry, micronemes and dense granules that discharge their contents during parasite invasion. The mucin-like glycoprotein GP900 with a single transmembrane domain is an immunodominant antigen and micronemal protein. It is relocated to the surface of excysted sporozoites and shed to form trails by sporozoites exhibiting gliding motility (gliding sporozoites). Read More

Hum Exp Toxicol 2022 Jan-Dec;41:9603271221089006

College of Life Sciences, 128790North China University of Science and Technology, China.

Eleutheroside B, also known as syringin, has been shown to have various pharmacological activities such as anti-inflammatory, anti-irradiation and antidepressant, but there are few studies on its anti-cancer activity. Its anti-tumor effect on SMMC-7721 cells has not been revealed. Moreover, whether it induces autophagy is still unclear. Read More