JTCVS Tech 2021 Apr 13;6:68-70. Epub 2021 Jan 13.
Division of Cardiovascular Surgery and Cardiology, Mayagüez Medical Center, Mayagüez, Puerto Rico.
Function (Oxf) 2021 19;2(5):zqab041. Epub 2021 Aug 19.
Department of Pharmacology, University of California Davis, Davis, CA 95616, USA.
Cigarette smoke, including secondhand smoke (SHS), has significant detrimental vascular effects, but its effects on myogenic tone of small resistance arteries and the underlying mechanisms are understudied. Although it is apparent that SHS contributes to endothelial dysfunction, much less is known about how this toxicant alters arterial myocyte contraction, leading to alterations in myogenic tone. The study's goal is to determine the effects of SHS on mesenteric arterial myocyte contractility and excitability. Read More
Arterioscler Thromb Vasc Biol 2021 Sep 23:ATVBAHA121316867. Epub 2021 Sep 23.
Departments of Molecular Cardiology and Cardiovascular and Metabolic Sciences, Lerner Research Institute, Cleveland Clinic, OH (A.A.T., V.P., S.-A.Y., C.F., Q.C., Q.W.).
Objective: Angiogenic factor AGGF1 (angiogenic factor and G-patch and FHA [Forkhead-associated] domain 1) promotes angiogenesis as potently as VEGFA (vascular endothelial growth factor A) and regulates endothelial cell (EC) proliferation, migration, specification of multipotent hemangioblasts and venous ECs, hematopoiesis, and vascular development and causes vascular disease Klippel-Trenaunay syndrome when mutated. However, the receptor for AGGF1 and the underlying molecular mechanisms remain to be defined. Approach and Results: Using functional blocking studies with neutralizing antibodies, we identified α5β1 as the receptor for AGGF1 on ECs. Read More
Kyobu Geka 2021 Sep;74(10):763-769
Division of Cardiovascular Surgery, Kobe University, Kobe, Japan.
We presented our experiences of reoperative aortic root replacement and technical details. Between April 2000 and February 2021, 80 patients underwent reoperative aortic root replacement (60 male, mean age 59.3±14. Read More
J Vis Exp 2021 Sep 3(175). Epub 2021 Sep 3.
Oregon Health & Science University;
Carotid artery injuries are serious complications of endoscopic endonasal surgery. As these occur rarely, simulation training offers an avenue for technique and algorithm development in resident learners. This study develops a realistic cadaveric model for the training of crisis resource management in the setting of cavernous carotid artery injury. Read More
J Card Surg 2021 Sep 19. Epub 2021 Sep 19.
Division of Cardiothoracic Surgery, Department of Surgery, University of Colorado, Aurora, Colorado, USA.
Pulmonary artery (PA) pseudoaneurysms are a rare but potentially lethal diagnosis. They can be further categorized by etiology or location and are typically successfully treated with endovascular therapies. However, they occasionally require operative intervention. Read More