Rev Port Cardiol 2021 Sep 20;40(9):703-705. Epub 2021 Jul 20.
CIBERCV, Cardiology Department, Hospital Clínico Universitario, Valladolid, Spain.
Bone 2021 Sep 15:116203. Epub 2021 Sep 15.
Department of Biomedicine, Aarhus University, Aarhus, Denmark.
Mountaineers at high-altitude are at increased risk of acute mountain sickness as well as high-altitude pulmonary and cerebral edema. A densitometric study in mountaineers has suggested that expeditions at high-altitude decrease bone mineral density. Surprisingly, the in vivo skeletal effects of hypobaric hypoxia are largely unknown, and have not been studied using advanced contemporary methods to assess bone microstructure. Read More
Exp Physiol 2021 Sep 17. Epub 2021 Sep 17.
Department of Cardiology, The First People's Hospital of Jingmen, Jingmen, 448000, China.
New Findings: What is the central question of this study? Does VNS have protective effects against both direct liver damage and distant lung injury in a hepatic ischemia/reperfusion rat model? What is the main finding and its importance? VNS provides the protective effects through anti-inflammation and anti-oxidative stress possibly achieved by the vagovagal reflex.Abstract: Hepatic ischemia reperfusion (I/R) is not an isolated event; instead, it can result in remote organ dysfunction. The aim of this study was to investigate whether vagal nerve stimulation (VNS) can alleviate hepatic I/R-induced lung injury and to explore the underlying mechanism. Read More
BMC Pulm Med 2021 Sep 16;21(1):293. Epub 2021 Sep 16.
Respiratory Medicine and Infectious Diseases, Faculty of Medicine, Oita University, 1-1 Idaigaoka, Hasama-machi, Yufu, Oita, 879-5593, Japan.
Background: Re-expansion pulmonary edema is an uncommon complication following drainage of a pneumothorax or pleural effusion. While pneumothorax is noted to complicate COVID-19 patients, no case of COVID-19 developing re-expansion pulmonary edema has been reported.Case Representation: A man in his early 40 s without a smoking history and underlying pulmonary diseases suddenly complained of left chest pain with dyspnea 1 day after being diagnosed with COVID-19. Read More
Vet Pathol 2021 Sep 16:3009858211042586. Epub 2021 Sep 16.
University of California, Davis, CA, USA.
A retrospective study of guinea pigs submitted for necropsy revealed intracytoplasmic inclusions in the cardiomyocytes of 26 of 30 animals. The inclusions were found with approximately the same frequency in male and female guinea pigs and were slightly more common in older animals. In most cases, the animals did not have clinical signs or necropsy findings suggestive of heart failure, and the cause of death or reason for euthanasia was attributed to concurrent disease processes. Read More
Int Immunopharmacol 2021 Sep 13;100:108106. Epub 2021 Sep 13.
Department of Emergency, Longhua Hospital Affiliated to Shanghai University of Chinese Medicine, China. Electronic address:
Background: NOD-like receptor protein 3 (NLRP3) inflammasome activation has emerged as a crucial contributor to sepsis-induced lung injury. Geranylgeranyl diphosphate synthase 1 (GGPPS1) reportedly exerts the pro-inflammatory capability via activation of NLRP3 inflammasome. However, little is known about the role and mechanism of GGPPS1 in sepsis-induced lung injury. Read More