Iran J Public Health 2021 May;50(5):1079-1081
Department of Microbiology and Applied Microbiology Research Center, Systems Biology and Poisonings Institute, Baqiyatallah University of Medical Sciences, Tehran, Iran.
Diseases 2021 Aug 27;9(3). Epub 2021 Aug 27.
Central Department of Microbiology, Tribhuvan University, Kirtipur 44600, Kathmandu, Nepal.
A urine dipstick test used for prompt diagnosis of urinary tract infection (UTI) is a rapid and cost-effective method. The main objective of this study was to compare the efficacy of the urine dipstick test with culture methods in screening for UTIs along with the detection of the gene in extended spectrum β-lactamase (ESBL)-producing . A total of 217 mid-stream urine samples were collected from UTI-suspected patients attending Bharatpur Hospital, Chitwan, and tested by dipstick test strip (COMBI-10SL, Germany) prior to the culture. Read More
BMJ Open 2021 Sep 24;11(9):e047957. Epub 2021 Sep 24.
Division of Life Sciences and Medicine, The First Affiliated Hospital of USTC, Hefei, Anhui, China
Objective: The neutrophil-to-lymphocyte ratio (NLR) is recognised as a suitable prognostic biomarker in patients with breast cancer. Nevertheless, the efficacy of this biomarker in predicting the pathological complete response (pCR) and survival in patients with breast cancer receiving neoadjuvant chemotherapy (NACT) is still controversial. This meta-analysis aimed to identify the association between baseline NLR and the prognosis of patients with breast cancer treated with NACT. Read More
Leuk Res 2021 Sep 20;110:106709. Epub 2021 Sep 20.
Department of Pathology, The First Affiliated Hospital of Zhengzhou University, No. 1 Jianshe Dong Road, Zhengzhou, 450052, Henan, People's Republic of China; Henan Province Key Laboratory of Tumor Pathology, Department of Pathology of The First Affiliated Hospital of Zhengzhou University, No. 40 Daxue Road, Zhengzhou, 450003, Henan, People's Republic of China. Electronic address:
Tumor-associated macrophages (TAMs) are closely associated with poor multiple myeloma (MM) prognosis. Therefore, in-depth understanding of the mechanism by which TAM supports MM progression may lead to its effective treatment. We used the MM nude mouse subcutaneous xenograft model to evaluate the efficacy of the macrophage-depleting agent clodronate liposome (Clo) against MM and elucidate the mode of action of this therapy. Read More
Br Poult Sci 2021 Sep 24. Epub 2021 Sep 24.
Joint International Research Laboratory of Agriculture & Agri-Product Safety of Ministry of Education, Yangzhou University, Yangzhou 225009, Jiangsu, China.
1. NOD1 is a significant member of the NOD-like receptor (NLR) family. Its main role is to identify microorganisms that invade the body, transmit immune signals and regulate innate immune responses. Read More
F1000Res 2020 24;9:1030. Epub 2020 Aug 24.
Department of Experimental Surgery, University of Heidelberg, Medical Faculty in Mannheim, Mannheim, Baden-Wuttenberg, 68167, Germany.
Accurate viral load (VL) determination is paramount to determine the efficacy of anti-HIV-1 therapy. The conventional method used, fit-point (FP), assumes an equal efficiency in the polymerase chain reaction (PCR) among samples that might not hold for low-input templates. An alternative approach, maxRatio, was introduced to compensate for inhibition in PCR. Read More