J Neural Transm (Vienna) 2021 Jun 19. Epub 2021 Jun 19.
Institut für Virologie und Immunbiologie, Universität Würzburg, Versbacherstraße Straße 7, 97078, Würzburg, Germany.
Fish Physiol Biochem 2021 Dec 4. Epub 2021 Dec 4.
Chronobiology Lab, Department of Physiology, Faculty of Biology, University of Murcia, Mare Nostrum Campus, IUIE, IMIB-Arrixaca, 30100, Murcia, Spain.
The longevity-homeoviscous adaptation (LHA) theory of ageing states that lipid composition of cell membranes is linked to metabolic rate and lifespan, which has been widely shown in mammals and birds but not sufficiently in fish. In this study, two species of the genus Amphiprion (Amphiprion percula and Amphiprion clarkii, with estimated maximum lifespan potentials [MLSP] of 30 and 9-16 years, respectively) and the damselfish Chromis viridis (estimated MLSP of 1-2 years) were chosen to test the LHA theory of ageing in a potential model of exceptional longevity. Brain, livers and samples of skeletal muscle were collected for lipid analyses and integral part in the computation of membrane peroxidation indexes (PIn) from phospholipid (PL) fractions and PL fatty acid composition. Read More
Brain Behav 2021 Dec 4:e2449. Epub 2021 Dec 4.
Division of Neuroradiology, Department of Diagnostics, Geneva University Hospitals, Geneva, Switzerland.
Background: Synthetic MRI (SyMRI) is a quantitative technique that allows measurements of T1 and T2 relaxation times (RTs). Brain RT evolution across lifespan is well described for the younger population. The aim was to study RTs of brain parenchyma in a healthy geriatric population in order to define the normal value of structures in this group population. Read More
Autism Res 2021 Dec 4. Epub 2021 Dec 4.
Dutch Autism & ADHD Research Center, Brain & Cognition, Department of Psychology, University of Amsterdam, Amsterdam, The Netherlands.
Findings on age-related cognitive effects in autism in adulthood are inconsistent across studies. As these studies substantially differ in their methodology, replication studies are needed. In this replication study frequentist (i. Read More
Epilepsia 2021 Dec 4. Epub 2021 Dec 4.
Melbourne School of Psychological Sciences, The University of Melbourne, Melbourne, Vic., Australia.
Objective: Identity is a multifaceted construct, comprising personal identity (sense of being a unique individual) and social identity (the sense-of-self derived from membership of social groups). Social identity involves explicit identification with a group ("I am …") and implicit behaviors or attitudes associated with group membership. Following successful treatment with surgery, patients with epilepsy can undergo a complex and lasting change in personal identity. Read More
Hum Brain Mapp 2021 Dec 4. Epub 2021 Dec 4.
Department of Complex Trait Genetics, Center for Neurogenomics and Cognitive Research, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.
Multiscale integration of gene transcriptomic and neuroimaging data is becoming a widely used approach for exploring the molecular underpinnings of large-scale brain organization in health and disease. Proper statistical evaluation of determined associations between imaging-based phenotypic and transcriptomic data is key in these explorations, in particular to establish whether observed associations exceed "chance level" of random, nonspecific effects. Recent approaches have shown the importance of statistical models that can correct for spatial autocorrelation effects in the data to avoid inflation of reported statistics. Read More