J Orthop Translat 2021 Mar 6;27:A1. Epub 2021 Apr 6.
Department of Orthopaedics and Traumatology, Faculty of Medicine, The Chinese University of Hong Kong, Shatin, Hong Kong, China.
Dev Neurobiol 2021 Jun 10. Epub 2021 Jun 10.
Instituto de Biología Celular y Neurociencias "Prof. E. De Robertis"(IBCN)- CONICET-Universidad de Buenos Aires, Buenos Aires, Argentina.
Leucine-rich repeat (LRR) transmembrane proteins have been directly linked to neurodevelopmental and cognitive disorders. We have previously shown that the LRR transmembrane protein Lrig1 is a physiological regulator of dendrite complexity of hippocampal pyramidal neurons and social behavior. In this study, we performed a battery of behavioral tests to evaluate spatial memory and cognitive capabilities in Lrig1 mutant mice. Read More
J Contin Educ Health Prof 2021 Apr;41(2):119-123
Mr. Thomas J. Van Hoof, MD, EdD: Associate Professor, University of Connecticut School of Nursing, Storrs, and Associate Professor, Department of Public Health Sciences, University of Connecticut School of Medicine, Farmington, CT. Mr. Christopher R. Madan, PhD: Assistant Professor, School of Psychology, University of Nottingham, Nottingham, United Kingdom. Ms. Megan A. Sumeracki, PhD: Assistant Professor, Department of Psychology, Rhode Island College, Rhode Island, United Kingdom.
Abstract: Retrieval practice is an evidence-based, science of learning strategy that is relevant to the planning and implementation of continuing professional development (CPD). Retrieval practice requires one to examine long-term memory to work with priority information again in working memory. Retrieval practice improves learning in two ways. Read More
Neuropsychiatr Dis Treat 2021 4;17:1311-1339. Epub 2021 May 4.
Department of Pathophysiology, Medical University of Gdansk, Gdansk, Poland.
Alzheimer's disease (AD) is the most common form of dementia and aging is the most common risk factor for developing the disease. The etiology of AD is not known but AD may be considered as a clinical syndrome with multiple causal pathways contributing to it. The amyloid cascade hypothesis, claiming that excess production or reduced clearance of amyloid-beta (Aβ) and its aggregation into amyloid plaques, was accepted for a long time as the main cause of AD. Read More
BMC Psychiatry 2021 04 29;21(1):216. Epub 2021 Apr 29.
Department of Psychiatry and Behavioural and Clinical Neuroscience Institute, University of Cambridge, Herchel Smith Building for Brain & Mind Sciences, Forvie Site, Robinson Way, Cambridge, CB2 0SZ, UK.
Background: Around 25 to 30% of patients with obsessive-compulsive disorder (OCD) do not respond to treatment. These patients have the longest duration of disease and the worst prognosis. Following years of research on this topic, insight has emerged as a potential explanation for this therapeutic resistance. Read More