Encephale 2021 Apr 13. Epub 2021 Apr 13.
EA 3279-EA 3279: CEReSS, Health Service Research and Quality of Life Center, Aix Marseille Univ, 27, boulevard Jean Moulin, 13005 Marseille, France; Department of Medical Information and Public Health, AP-HM, Aix Marseille Univ, 27, boulevard Jean Moulin, 13005 Marseille, France; Fondation FondaMental, Créteil, France. Electronic address:
Eur Arch Psychiatry Clin Neurosci 2021 Jan 3. Epub 2021 Jan 3.
Translational Neuropsychology and Applied Cognitive Neuroscience Laboratory, Shanghai Mental Health Centre, Shanghai Jiao Tong University School of Medicine, 600 Wan Ping Nan Road, Shanghai, 200030, China.
The prevalence of obsessive-compulsive symptoms (OCS) in schizophrenia patients is as around 30%. Evidence suggested that mild OCS could reduce symptoms of schizophrenia, supporting the presence of compensatory functions. However, severe OCS could aggravate various impairments in schizophrenia patients, supporting the "double jeopardy hypothesis". Read More
CNS Spectr 2020 Jul 27:1-13. Epub 2020 Jul 27.
Department of Mental Health, AsFO Friuli Occidentale, Italian NHS, Pordenone, Italy.
Obsessive-compulsive disorder (OCD) is a chronic and disabling mental disorder characterized by the presence of obsessions and/or compulsions that cause major distress and impair important areas of functioning. About 9 out of 10 patients with OCD have comorbid psychiatric diagnoses. A high proportion of clinically diagnosed OCD patients fulfill diagnostic criteria of a schizophrenia spectrum disorder, to the point that significant evidence in the literature supports the existence and the clinical relevance of a schizo-obsessive spectrum of disorders, including schizotypal personality disorder (SPD) with OCD (schizotypal OCD). Read More
Asian J Psychiatr 2020 Aug 14;52:102096. Epub 2020 Apr 14.
Neuropsychology and Applied Cognitive Neuroscience Laboratory, CAS Key Laboratory of Mental Health, Institute of Psychology, Beijing, 100101, PR China; Sino-Danish College, University of Chinese Academy of Sciences, Beijing, 100190, PR China; Sino-Danish Center for Education and Research, Beijing, 100190, PR China; Department of Psychology, University of Chinese Academy of Sciences, Beijing, PR China. Electronic address:
Altered brain structures have been found in patients with schizo-obsessive disorder, schizophrenia and obsessive-compulsive disorder in previous studies. However, it is unclear whether similar brain changes are also found in individuals with high schizo-obsessive traits (SOT), high schizotypal traits (SCT) and obsessive-compulsive symptoms (OCS). We examined grey matter volume (GMV) and white matter integrity (WMI, including fractional anisotropy, mean diffusivity, axial diffusivity and radial diffusivity) in 26 individuals with high SOT, 30 individuals with high SCT, 25 individuals with OCS and 30 individuals with low trait scores (LT) in this study. Read More
Brain Stimul 2020 May - Jun;13(3):858-860. Epub 2020 Mar 11.
WISER Neuromodulation Program, Department of Psychiatry, National Institute of Mental Health and Neurosciences, Bangalore, India.
Transcranial direct current stimulation (tDCS) is a type of non-invasive brain stimulation technique that is explored as an add-on treatment for the alleviation of symptoms across the diverse symptom domains in neuropsychiatric disorders. In psychiatry, data is emerging on the effects of tDCS as an add-on treatment in schizophrenia as well as obsessive-compulsive disorder (OCD). But despite high prevalence, the effectiveness of tDCS in co-morbid schizophrenia and OCD is lacking. Read More