Arch Bronconeumol 2021 Apr 24;57 Suppl 2:59-61. Epub 2021 Feb 24.
Respiratory Institute, Hospital Clinic, University of Barcelona, C/Villaroel 170, 08036 Barcelona, Spain; Centro de Investigación Biomédica en Red de Enfermedades Respiratorias (CIBER), Spain; Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), C/Roselló 149, 08036 Barcelona, Spain.
Ann Allergy Asthma Immunol 2021 Sep 19. Epub 2021 Sep 19.
Department of Respiratory and Critical Care Medicine, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. Electronic address:
Background: The clinical significance of small-airway dysfunction (SAD) determined with spirometry in patients with normal FEV1& FEV1/FVC is controversial.Objective: This study aimed to determine whether SAD presents histological abnormalities in the setting of normal CT imaging and FEV1& FEV1/FVC.Methods: A cross-sectional study was performed in 64 patients undergoing thoracotomy for pulmonary nodules. Read More
J Cell Mol Med 2021 Sep 22. Epub 2021 Sep 22.
Department of Geriatrics, The Central Hospital of Wuhan, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Circular RNA is a newly discovered member of non-coding RNA (ncRNA) and regulates the target gene by acting as a micro-RNA sponge. It plays vital roles in various diseases. However, the functions of circular RNA in non-small cell lung cancer (NSCLC) remain still unclear. Read More
Eur J Prev Cardiol 2021 Sep;28(11):1269-1278
Department of Pediatric Cardiology, Erasmus MC-Sophia Children's Hospital, The Netherlands.
Background: Patients with a Fontan circulation have a reduced exercise capacity, which is an important prognostic predictor of morbidity and mortality. A way to increase exercise capacity in Fontan patients might be exercise training. This systematic review assesses the effects of exercise training investigated in Fontan patients in order to provide an overview of current insights. Read More
Am J Physiol Cell Physiol 2021 Sep 22. Epub 2021 Sep 22.
Department of Physiology and Cell Biology, The Dorothy M. Davis Heart and Lung Research Institute, The Ohio State University College of Medicine, Columbus OH, United States.
Mitochondria have been recognized as key organelles in cardiac physiology and are potential targets for clinical interventions to improve cardiac function. Mitochondrial dysfunction has been accepted as a major contributor to the development of heart failure. The main function of mitochondria is to meet the high energy demands of the heart by oxidative metabolism. Read More
Cochrane Database Syst Rev 2021 Sep 22;9:CD010288. Epub 2021 Sep 22.
Department of Pathology, University College of Medical Sciences (UCMS), Delhi, India.
Background: Cystic fibrosis is an autosomal recessive multisystem disorder with an approximate prevalence of 1 in 3500 live births. Allergic bronchopulmonary aspergillosis is a lung disease caused by aspergillus-induced hypersensitivity with a prevalence of 2% to 15% in people with cystic fibrosis. The mainstay of treatment includes corticosteroids and itraconazole. Read More