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Colloids Surf B Biointerfaces 2021 Mar 31;203:111725. Epub 2021 Mar 31.

Biomedical Engineering Department, Amirkabir University of Technology (Tehran Polytechnic), Tehran, Iran.

Hydrogels are a promising choice for soft tissue (cartilage, skin and adipose) engineering and repair. However, lack of interconnected porosity and poor mechanical performance have hindered their application, especially in natural polymer-based hydrogels. Cryogels with the potential to overcome the shortcomings of hydrogels have drawn attention in the last few years. Read More

Colloids Surf B Biointerfaces 2021 Apr 3;203:111742. Epub 2021 Apr 3.

Laboratory of Biomaterial Surfaces & Interfaces, Institute of New Carbon Materials, College of Materials Science and Engineering, Taiyuan University of Technology, Taiyuan, 030024, China. Electronic address:

Angiogenesis is critical for tissue repair and regeneration, including implant osseointegration. It is well known that macrophages exert immunomodulatory functions in angiogenesis. However, whether macrophage-derived exosomes participate in the process is still unclear. Read More

Neuroimage Clin 2021 Mar 29;30:102650. Epub 2021 Mar 29.

Centre for the Developing Brain, King's College London, London, UK.

Background: Infants born preterm are at increased risk of neurological complications resulting in significant morbidity and mortality. The exact mechanism and the impact of antenatal factors has not been fully elucidated, although antenatal infection/inflammation has been implicated in both the aetiology of preterm birth and subsequent neurological sequelae. It is therefore hypothesized that processes driving preterm birth are affecting brain development in utero. Read More

Biomaterials 2021 Mar 26;272:120772. Epub 2021 Mar 26.

Institute of Analytical Chemistry, Department of Chemistry, Zhejiang University, Hangzhou, 310058, China. Electronic address:

Insufficient angiogenesis happened in body defects such as ulceration, coronary heart disease, and chronic wounds constitutes a major challenge in tissue regeneration engineering. Owing to the poor bioactivity and maintenance of pro-angiogenic cells and factors during transplantation, new bioactive materials to tackle the barrier are highly desirable. Herein, we demonstrate a co-delivery platform for synergistic promotion of angiogenesis based on biodegradable, therapeutic, and self-reporting luminescent porous silicon (PSi) microparticles. Read More

J Mech Behav Biomed Mater 2021 Apr 2;119:104476. Epub 2021 Apr 2.

Department of Mechanical Engineering, Politecnico di Milano, Milan, Italy.

Impact based surface treatments with adequate kinetic energy have favorable effects on promoting cell-substrate interactions, reducing bacterial adhesion, and enhancing fatigue performance of metallic biomaterials. Here, we used both numerical and experimental approaches to evaluate the potential of these treatments for addressing the major issue associated with the application of pure iron in biomedical implants, i.e. Read More