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Biomech Model Mechanobiol 2021 Mar 2. Epub 2021 Mar 2.

Theoretical and Applied Mechanics, Northwestern University, 2145 Sheridan Road, Evanston, IL, 60208, USA.

Fluoroscopy is a radiographic procedure for evaluating esophageal disorders such as achalasia, dysphasia and gastroesophageal reflux disease. It performs dynamic imaging of the swallowing process and provides anatomical detail and a qualitative idea of how well swallowed fluid is transported through the esophagus. In this work, we present a method called mechanics informed fluoroscopy (FluoroMech) that derives patient-specific quantitative information about esophageal function. Read More

Regen Ther 2020 Dec 10;15:323-331. Epub 2020 Dec 10.

Institute of Advanced Biomedical Engineering and Science, Tokyo Women's Medical University, Japan.

Background: The utility of endoscopic transplantation of epithelial cell sheets to ulcer sites after endoscopic submucosal dissection (ESD) has been shown to prevent scar stenosis after ESD of early esophageal cancer. Previously, our group reported use of an endoscopic transplantation device fabricated with a 3-dimensional printer. Cell sheets are transplanted to the esophageal wound site with the following procedure: first, a cell sheet harvested from temperature-responsive culture dishes is placed on the device's deflated balloon surface and transported to the wound site with endoscopic forceps; second, by applying pressure from inflating the balloon locally at the wound site, the cell sheet is successfully transferred and adhered to the wound tissue; third, the balloon is deflated, and the device is removed. Read More

Ear Nose Throat J 2020 Sep 14:145561320953707. Epub 2020 Sep 14.

Division of Otolaryngology-Head and Neck Surgery, Cooper University Hospital, Camden, NJ, USA.

A 32-year-old female with a history of bipolar disorder and schizophrenia was transported to our tertiary-care hospital after swallowing a large toilet paper holder bracket. Removal of the large foreign body required coordination between anesthesiology, otolaryngology, and trauma surgery. A tracheostomy airway was established, and the object was removed transorally. Read More

Regen Ther 2020 Jun 16;14:87-94. Epub 2020 Jan 16.

Institute of Advanced Biomedical Engineering and Science, Tokyo Women's Medical University (TWIns), 8-1 Kawada-Cho, Shinjuku-ku, Tokyo, 162-8666, Japan.

Introduction: Cultured stratified epithelial cell sheets have been clinically utilized as transplantable grafts for the regeneration of epithelial tissues, such as the esophagus, cornea, skin, and intraoral cavity. These cell sheets are expected to gain widespread use as regenerative medicine products and save many patients. For this purpose, establishing and disseminating the stale protocol of fabricating the cell sheet is crucial. Read More

Mil Med 2020 08;185(7-8):e1329-e1333

Department of Military and Emergency Medicine, F. Edward Hébert School of Medicine, Uniformed Services University of Health Sciences, 4301 Jones Bridge Rd., Bethesda, MD 20814.

A 17-month-old male presented to a community hospital emergency department in respiratory distress suggestive of reactive airway exacerbation or pneumonia. He rapidly deteriorated into fulminant respiratory failure with multilobar atelectasis. He was managed with continuous albuterol, intravenous antibiotics, corticosteroids, intubation, and vasopressors. Read More