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Cureus 2021 Mar 10;13(3):e13800. Epub 2021 Mar 10.

Interventional Cardiology, Apex Heart Institute, Ahmedabad, IND.

Introduction The 60/60 sign in 2D transthoracic echocardiography (TTE) - a combination of pulmonary acceleration time (PAT) less than 60 milliseconds and tricuspid regurgitation (TR) jet gradient of less than 60 mmHg - has been found to be specific for the diagnosis of pulmonary embolism (PE). Materials and methods An observational prospective analysis was carried out on cases of suspected PE presenting to the emergency room (ER). TTE was performed on all cases with suspected PE prior to computed tomography pulmonary angiography (CTPA). Read More

Polymers (Basel) 2021 Mar 9;13(5). Epub 2021 Mar 9.

National Institute of Chemistry, Hajdrihova 19, 1000 Ljubljana, Slovenia.

Self-healing anticorrosion composite coatings containing isophorone diisocyanate-loaded polyurethane microcapsules were developed, and comprehensive research on prepolymer and microcapsules synthesis, as well as functional composite coatings preparation and characterization, was performed. The influence of the prepolymer type and the concentration of the stabilizing agent used in the synthesis procedure on the properties of the microcapsules was studied in detail. For this purpose, three different prepolymers were prepared from toluene-2,4-diisocyanate (TDI) and either glycerol, 1,4-butanediol, or 1,6-hexanediol, and their chemical properties were investigated. Read More

Ginekol Pol 2021 10;92(3):195-204. Epub 2021 Mar 10.

Department of Obstetrics and Gynecology, Saglik Bilimleri University, Kanuni Sultan Suleyman Training and Research Hospital, Istanbul, Turkey.

Objectives: The primary aim of this study was to evaluate fetal cardiac systolic and diastolic function using the tissue Doppler technique in pregnancies with complications of fetal growth restriction (FGR) and to examine the relationship between FGR with umbilical artery Doppler parameters and fetal cardiac function in complicated pregnancies.

Material And Methods: This study included 30 pregnant women with FGR complications and 46 pregnant women without FGR complications. Both groups were at 24-34 gestational weeks. Read More

Pharmaceuticals (Basel) 2021 Feb 27;14(3). Epub 2021 Feb 27.

Department of Clinical Pharmacy and Pharmacy Administration, College of Pharmacy, Fudan University, Shanghai 201203, China.

Wuzhi capsule (WZC) is commonly prescribed with tacrolimus in China to ease drug-induced hepatotoxicity. Two abundant active ingredients, schisantherin A (STA) and schisandrin A (SIA) are known to inhibit CYP3A enzymes and increase tacrolimus's exposure. Our previous study has quantitatively demonstrated the contribution of STA and SIA to tacrolimus pharmacokinetics based on physiologically-based pharmacokinetic (PBPK) modeling. Read More

Clin Hemorheol Microcirc 2021 Feb 26. Epub 2021 Feb 26.

Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Department of Radiology, Berlin, Germany.

Background: Tissue Doppler imaging (TDI) uses the Doppler principle to quantify the movement of biological tissues.

Objective: To investigate the contribution of TDI parameters derived during magnetic resonance imaging and ultrasound (MRI/US) fusion-guided biopsy for prostate cancer (PCa) discrimination.

Methods: From March 2016 to Dec. Read More