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Sci Rep 2021 Apr 8;11(1):7804. Epub 2021 Apr 8.

Collaborative Innovation Center of Yangtze River Delta Region Green Pharmaceuticals, College of Pharmaceutical Sciences, Zhejiang University of Technology, Hangzhou, China.

Sulforaphane (SFN), a naturally-occurring isothiocyanate enriched in cabbage and broccoli, has been provided as food supplements to improve weight management and reduce lipid levels. However, its effects on serum lipid profiles are contradictory. In this review, a meta-analysis and systematic review of SFN on lipid reduction and weight control is assessed with mice and rats fed on high-fat diet. Read More

Clin Chim Acta 2021 Apr 3;518:134-141. Epub 2021 Apr 3.

Department of Cardiology, The Xiamen Cardiovascular Hospital of Xiamen University, Xiamen, Fujian, China. Electronic address:

Hyperlipidemia is correlated with several health problems that contain the combination of hypertension, obesity, and diabetes mellitus, which are grouped as metabolic syndrome. Though the lipid-lowering agents, such as statins, which aims to reduce serum low-density lipoprotein cholesterol (LDL-C) has been considered as one of the most effective therapeutics in treating hyperlipidemia and coronary artery diseases, the persistent high risk of atherosclerosis after intensive lipid-lowering therapy could not be simply explained by hyperlipidemia. Therefore, it is necessary to identify novel factors to manage treatment and to predict risk of cardio-metabolic events. Read More

Front Nutr 2021 19;8:647847. Epub 2021 Mar 19.

Department of Health and Nutritional Sciences, South Dakota State University, Brookings, SD, United States.

To examine the response of a calorie-restricted Dietary Approaches to Stop Hypertension diet on indicators of cardiometabolic health in a cohort of sedentary obese older adults. This was a controlled-feeding trial with a parallel design. Each participant consumed either 3 oz (85 g; = 15) or 6 oz (170. Read More

Int J Clin Pract 2021 Apr 4:e14207. Epub 2021 Apr 4.

Department of Cardiology, Renmin Hospital, Hubei University of Medicine, Shiyan, Hubei, 442000, China.

Background: To observe the correlation of osteoprotegerin, soluble receptor activator of nuclear factor-κB ligand (sRANKL), inflammatory factors and epicardial adipose tissue volume (EATV) with the severity of coronary heart disease (CHD).

Methods: We studied 390 patients who were admitted to the Department of Cardiology of our hospital because of chest pain and underwent coronary angiography (CAG) from August 2018 to December 2019. According to CAG, 209 patients had non-CHD and 181 patients had CHD. Read More

Nutr Metab Cardiovasc Dis 2021 Feb 15. Epub 2021 Feb 15.

Department of Cardiology, Guangdong Cardiovascular Institute, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangzhou 510080, China. Electronic address:

Background And Aims: The relationship between lipid variability and stroke among patients with hypertension were inconclusive. We aimed to investigate the association of lipid variability with ischemic stroke in hypertensive patients.

Methods And Results: This retrospective cohort study included 4995 individuals with hypertension between 2013 and 2015, and recorded their status of ischemic stroke until the end of 2018. Read More