Gene 2021 May 23;781:145534. Epub 2021 Feb 23.
Department of General Surgery, Tongren Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200336, China. Electronic address:
J Surg Res 2021 Apr 10;264:327-333. Epub 2021 Apr 10.
Department of Surgery, University of California San Diego, San Diego, California; Department of Surgery, VA San Diego Healthcare System, San Diego, California. Electronic address:
Background: It is difficult to distinguish between a tumor and its liver segment with traditional use of indocyanine green (ICG) alone. In the present study, a method was used to limit ICG to the liver segment adjacent to a tumor. A spectrally-distinct fluorescently-labeled tumor-specific antibody against human carcinoembryonic antigen-related cell-adhesion molecules was used to label the metastatic tumor in a patient-derived orthotopic xenograft mouse model to enable color-coded visualization and distinction of a colon-cancer liver metastases and its adjacent liver segment. Read More
Bratisl Lek Listy 2021 ;122(5):347-356
Objectives: The aim of this study was to analyze the effect of water load test (WLT) on heart rate variability (HRV), blood pressure variability (BPV), hemodynamic parameters and gastric myoelectric activity in gastrointestinal (GI) cancer patients.Background: WLT activates gastrointestinal mechanoreception and osmoreception, and hence, can indirectly modulate autonomic activity.Methods: Eighty patients (mean age 61. Read More
Colorectal Dis 2021 Apr 13. Epub 2021 Apr 13.
Aims: Little is known about colorectal cancer treatment delivery in India and associated costs. The aim of this study is to identify financial and non-financial barriers for colorectal cancer treatment adherence in India.Methods: CROCODILE is a mixed-methods with a quantitative and a qualitative workstream. Read More
Surg Case Rep 2021 Apr 13;7(1):89. Epub 2021 Apr 13.
Department of Gastroenterological Surgery, Saitama Medical University International Medical Center, 1397-1 Yamane, Hidaka-shi, Saitama, 350-1298, Japan.
Background: We have introduced the Senhance Digital Laparoscopy System and actively use for colorectal cancer surgery. Recently, we also try to perform surgery by reduce port as less invasive method. For the first time, we report a case of single-incision plus one-port transverse colectomy using Senhance system. Read More
Arch Toxicol 2021 Apr 13. Epub 2021 Apr 13.
Department of Environmental Genomics, Jiangsu Key Laboratory of Cancer Biomarkers, Prevention and Treatment, Collaborative Innovation Center for Cancer Personalized Medicine, Nanjing Medical University, Nanjing, China.
The programmed cell death-1 (PD-1)/cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) immune checkpoint pathways serve as targets of immunotherapy for colorectal cancer. However, the associations between genetic variations in these pathways and colorectal cancer risk, prognosis, and immune status remain unclear. The associations between single-nucleotide polymorphisms (SNPs) and colorectal cancer risk and survival were evaluated in a case-control study comprising 1150 cases and 1342 controls along with 287 cases with overall survival information. Read More