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Pharmacology 2021 Apr 13:1-11. Epub 2021 Apr 13.

Pharmacological Research Center of Medicinal Plants, Mashhad University of Medical Sciences, Mashhad, Iran.

Background: Our liver has a variety of vital functions including removing poisons, storing energy, immunological roles, and secretory and excretory functions. It may face some kinds of diseases caused by viruses, hepatotoxic chemicals, drugs, alcohol, and inherited disorders. Oxidative stress and inflammation are in the core of mechanisms of liver damages induced by viruses or chemical agents. Read More

Virus Res 2021 Apr 3;298:198411. Epub 2021 Apr 3.

Mustafa Kemal University, Plant Protection Department, Hatay, 31034, Turkey.

A virus-like disease with symptoms including mosaic structure, deformation, vein clearing and necrosis on the leaves and deformation, crumbling, and scab on the fruits was detected in black mulberry trees (Morus nigra L.) in Kayseri province of Turkey. A novel positive single-stranded RNA virus with a bipartite genome and the mulberry badnavirus 1 (MBV-1) were detected in the black mulberry trees by high throughput sequencing and bioinformatic analyses. Read More

Open Life Sci 2020 10;15(1):318-325. Epub 2020 Jun 10.

State Key Laboratory for Conservation and Utilization of Subtropical Agro-bioresources (South China Agricultural University), Guangdong Key Laboratory for Innovative Development and Utilization of Forest Plant Germplasm, Guangdong Province Research Center of Woody Forage Engineering Technology, College of Forestry and Landscape Architecture, South China Agricultural University, Guangzhou 510642, China.

Paper mulberry () is a tree species that has many economic, ecological, and social uses. This study developed an efficient protocol for regenerating shoots from leaf explants using Murashige and Skoog (MS) medium supplemented with different concentrations of plant growth regulators (PGRs), which play vital roles in shoot regeneration. The best result, 86. Read More

Arch Immunol Ther Exp (Warsz) 2021 Apr 3;69(1):10. Epub 2021 Apr 3.

N.F. Gamaleya National Research Center of Epidemiology and Microbiology of the Ministry of Health of Russia, Gamaleya 18, Moscow, Russia, 123098.

The review discusses a new approach to the prevention and treatment of viral infections based on the use of pine needles polyprenyl phosphate (PPP) and associated with the infringement of prenylation process-the attachment of farnesol or geranyl geraniol to the viral protein. Currently, prenylation has been detected in type 1 adenovirus, hepatitis C virus, several herpes viruses, influenza virus, HIV. However, this list is far from complete, given that prenylated proteins play an extremely important role in the activity of the virus. Read More