Search Our Scientific Publications & Authors

J Hypertens 2021 Apr 14. Epub 2021 Apr 14.

Department of Pediatric and Adolescents Medicine, Akershus University Hospital, Lørenskog, Norway MRC Lifecourse Epidemiology Unit, University of Southampton, Southampton, UK Institute of Clinical Medicine, University of Oslo, Campus AHUS, Lørenskog, Norway NIHR Southampton Biomedical Research Centre, University of Southampton and University Hospital Southampton NHS Foundation Trust, Southampton Vascular Physiology Unit, Institute of Cardiovascular Science, University College London, London Institute of Developmental Sciences, University of Southampton, Southampton, UK.

Objective: In children aged 8--9 years, we examined the associations of linear and abdominal circumference growth during critical stages of prenatal and postnatal development with six vascular measurements commonly used as early markers of atherosclerosis and later cardiovascular disease (CVD) risk.

Methods: In 724 children from the UK Southampton Women's Survey mother--offspring cohort, offspring length/height and abdominal circumference measurements were collected at 10 ages between 11 weeks' gestation and age 8--9 years. Using residual growth modelling and linear regression, we examined the independent associations between growth and detailed vascular measures made at 8--9 years. Read More

Cardiorenal Med 2021 Apr 14:1-10. Epub 2021 Apr 14.

Division of Cardiovascular Medicine, Department of Internal Medicine, University of Michigan Medical School and Michigan Medicine, Ann Arbor, Michigan, USA.

Introduction: Pulmonary hypertension is common among patients with end-stage renal disease, although data regarding the impact of right ventricular (RV) failure on postoperative outcomes remain limited. We hypothesized that echocardiographic findings of RV dilation and dysfunction are associated with adverse clinical outcomes after renal transplant.

Methods: A retrospective review of adult renal transplant recipients at a single institution from January 2008 to June 2010 was conducted. Read More

Physiol Meas 2021 Apr 14. Epub 2021 Apr 14.

Department of Cardiovascular Sciences, University of Leicester, Leicester, UNITED KINGDOM OF GREAT BRITAIN AND NORTHERN IRELAND.

Objective: Cerebral autoregulation impairment in acute neurovascular disease is well described. The recent BREATHE-ICH study demonstrated improvements in dynamic cerebral autoregulation, by hypocapnia generated by hyperventilation, in the acute period following intracranial haemorrhage (ICH). This exploratory analysis of the BREATHE-ICH dataset aims to examine the differences in hypocapnic responses between healthy controls and patients with ICH, and determine whether haemodynamic indices differ between baseline and hypocapnic states. Read More

Sleep Med Rev 2021 Mar 13;57:101473. Epub 2021 Mar 13.

Department of Neurology Sleep Disorders Center, University of Michigan Ann Arbor, MI, USA.

Obstructive sleep apnea (OSA) is the most common form of sleep-disordered breathing characterized by intermittent partial or complete closure of the upper airway during sleep. If left untreated, OSA is associated with adverse cardiovascular outcomes such as hypertension, coronary heart disease, heart failure, cardiac arrhythmia, stroke, and death. Positive airway pressure (PAP) is often considered the first-line treatment for OSA. Read More

J Hosp Infect 2021 Apr 11. Epub 2021 Apr 11.

Department of Microbiology, Institute of Biological Sciences, Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais, Brazil. Electronic address:

Background: SARS-CoV-2 predisposes patients to secondary infections; however, a better understanding of the impact of coinfections on the outcome of hospitalized COVID-19 patients is still necessary.

Aim: To analyse death risk due to coinfections in COVID-19 patients.

Methods: We evaluated the Odds of death of 212 severely ill COVID-19 patients, with detailed focus on the risks for each pathogen, site of infection, comorbidities and length of hospitalization. Read More