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ACS Infect Dis 2021 Apr 14. Epub 2021 Apr 14.

Department of Food and Animal Biotechnology, Seoul National University, Seoul 08826, Republic of Korea.

Microbes support their growth in vertebrate hosts by exploiting a large variety of dietary components as nutrients, which determines the composition of gut microbiota. A pathogen expands by utilizing 1,2-propanediol, a microbiota-fermented product, during mucosal inflammation. However, it remains largely unknown how the pathogen decides which nutrient to consume from the complex mixture in the gut. Read More

J Pediatr Gastroenterol Nutr 2021 Apr 12. Epub 2021 Apr 12.

Comparative Pediatrics and Nutrition, Department of Veterinary and Animal Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark; Department of Neonatology, Shenzhen People's Hospital (The Second Clinical Medical College, Jinan University; The First Affiliated Hospital, Southern University of Science and Technology), Shenzhen, Guangdong, China; Department of Neonatology, Rigshospitalet, Copenhagen, Denmark; Hans Christian Andersen Children's Hospital, Odense, Denmark.

Objectives: Exclusive feeding with bovine colostrum (BC) protects preterm pigs against necrotizing enterocolitis (NEC) and BC has recently been tested as a supplement to mother's own milk or formula (FOR) for very preterm infants. Using preterm pigs as model for infants, we investigated if BC has gut- and NEC-protective effects at different proportions of the daily enteral intake given as BC.

Methods: Sixty-eight caesarean-delivered preterm piglets (90% gestation) were allocated into four groups with increasing proportions of eight daily bolus feedings as BC: BC00 (only FOR feeding), BC25 (25% BC), BC50 (50% BC), or BC75 (75% BC). Read More

Am J Ther 2021 Apr 7. Epub 2021 Apr 7.

Carol Davila University of Medicine and Pharmacy, Department of Internal Medicine, Bucharest, Romania; and Cardiology Department, Colentina University Hospital, Bucharest, Romania.

Background: Atrial fibrillation (AF) is the most frequent sustained arrhythmia. It increases the risk of stroke, heart failure, death, hospitalizations, and costs.

Area Of Uncertainty: Several scores were introduced to stratify the stroke risk and need for anticoagulation in patients (pts) with AF . Read More

Gynecol Oncol Rep 2021 May 23;36:100752. Epub 2021 Mar 23.

Department of Obstetrics and Gynecology, Section of Gynecologic Oncology, University of Chicago, Chicago, IL, USA.

Cowden syndrome is a rare hereditary cancer syndrome characterized by a germline mutation which results in an increased risk of developing breast, thyroid, and endometrial carcinoma, as well as widespread benign hamartomas. Phyllodes tumor (PT) is a rare fibroepithelial tumor that accounts for less than 1% of all breast tumors. As mammary-type glands can be found in the anogenital region, PTs can rarely arise in this location. Read More

Biofabrication 2021 Apr 13. Epub 2021 Apr 13.

Seoul National University Bundang Hospital, bundang-gu, Seongnam, 13620, Korea (the Republic of).

During thyroid surgery, some parathyroid glands fail to maintain their function, therefore, they are unavoidably detached from the patient. For the purpose of re-preservation of the function, they are minced into small segments and transplanted into the fat or muscle layer. Yet, this method of auto-grafting the parathyroid glands is frequently unsuccessful due to its poor interaction and engraftment with the native tissue, eventually leading to the dysfunction of the parathyroid hormone (PTH) secretion. Read More