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AME Case Rep 2021 25;5. Epub 2021 Jan 25.

Palliative Medical Unit, Grantham Hospital, Hong Kong, China.

Pulmonary arterial hypertension (PAH) is an uncommon but potentially life-threatening illness. The elevated pulmonary arterial blood pressure will lead to right heart failure and even cardiopulmonary collapse if it is severe. Apart from general supportive measures, pulmonary hypertension-specific therapies (PHST) are available to slow down disease progression, but they are not curative. Read More

Cureus 2021 Feb 15;13(2):e13357. Epub 2021 Feb 15.

Anaesthesiology, Tata Main Hospital, Jamshedpur, IND.

Background: Coronavirus disease 2019 (COVID-19) infection is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), a single-stranded ribonucleic acid (RNA) β-coronavirus. Prolonged duration of symptoms, ill health, disability, and need for hospitalisation are all well-known features of severe COVID-19 disease.

Objective: To describe the epidemiological, clinical and imaging characteristics of hospitalised patients of COVID-19 who required prolonged oxygen therapy after testing negative for SARS-CoV-2 and attempt to determine the associated factors leading to delayed recovery, failure to wean, and mortality. Read More

J Pain Symptom Manage 2021 Feb 22. Epub 2021 Feb 22.

Cardiology Section, Department of Medicine, Boston VA Healthcare System, Boston, MA. Electronic address:

Context: Palliative care (PC) improves outcomes in noncancer illness. We hypothesized the benefit is driven by studies of heart failure (HF) patients exclusively versus studies of other noncancer illnesses.

Objectives: To assess difference in outcomes in trials with HF patients exclusively vs studies of other noncancer chronic illness. Read More

Cureus 2021 Feb 16;13(2):e13381. Epub 2021 Feb 16.

Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, USA.

Background Racial inequities in mortality and readmission for heart failure (HF) are well documented. Inequitable access to specialized cardiology care during admissions may contribute to inequity, and the drivers of this inequity are poorly understood. Methodology This prospective observational study explored proposed drivers of racial inequities in cardiology admissions among Black, Latinx, and white adults presenting to the emergency department (ED) with symptoms of HF. Read More

Surgery 2021 Feb 20. Epub 2021 Feb 20.

Department of Orthopedics and Trauma, Peking University People's Hospital, Beijing, China. Electronic address:

Background: Despite the improvement of surgical procedures and perioperative management, a portion of patients were still at high risk for intensive care unit admission owing to severe morbidity after hip fracture surgeries. The purpose of this study was to analyze influencing factors and to construct a clinical nomogram to predict unscheduled intensive care unit admission among inpatients after hip fracture surgeries.

Methods: We enrolled a total of 1,234 hip fracture patients, with 40 unplanned intensive care unit admissions, from January 2011 to December 2018. Read More