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J Neurol Surg B Skull Base 2021 Apr 30;82(2):258-263. Epub 2019 Sep 30.

Department of Neurosurgery, The Second Affiliated Hospital of Nanjing Medical University, Nanjing, People's Republic of China.

 Hypertensive intracerebral hemorrhage is one of the most common cerebrovascular diseases with high mortality and high disability rate. The aim of this study was to observe the curative effect of minimally invasive liquefaction and drainage of hypertensive putaminal hemorrhage (HPH) through frontal approach.  This study retrospectively reviewed the clinical data of 66 HPH patients who underwent surgery from January 2012 to January 2017 including 35 males and 31 females, aged 51 to 82 years, with an average age of 61. Read More

Vavilovskii Zhurnal Genet Selektsii 2020 Aug;24(5):525-532

Institute of Cytology and Genetics of Siberian Branch of the Russian Academy of Sciences, Novosibirsk, Russia.

Cell migration is an important morphogenetic process necessary at different stages of individual development and body functioning. The initiation and maintenance of the cell movement state requires the activation of many factors involved in the regulation of transcription, signal transduction, adhesive interactions, modulation of membranes and the cytoskeleton. However, cell movement depends on the status of both migrating and surrounding cells, interacting with each other during movement. Read More

Zhongguo Dang Dai Er Ke Za Zhi 2021 Jan;23(1):103-110

Department of Neonatology, First Affiliated Hospital of Xinjiang Medical University, Urumqi 830054, China.

Objective: To study the role of vascular endothelial growth factor-A (VEGF-A) in pulmonary vascular remodeling in neonatal rats with hypoxic pulmonary hypertension (HPH) by regulating survivin (SVV).

Methods: A total of 96 neonatal rats were randomly divided into three groups: HPH+VEGF-A group, HPH group, and control group. Each group was further randomly divided into 3-, 7-, 10-, and 14-day subgroups (=8 in each subgroup). Read More

ACS Biomater Sci Eng 2020 05 24;6(5):3122-3131. Epub 2020 Apr 24.

Department of Electronic Engineering, Chang Gung University, Taoyuan 33302, Taiwan.

In this present work, a plasmonic sensor is developed through an extremely cheap cellulose-based source, widely known as a food product, nata de coco (NDC). Capturing its interesting features, such as innate surface roughness from naturally grown cellulose during its fermentation period, the engineering and modulation of NDC fibril size and properties were attempted through a high-pressure homogenization (HPH) treatment to obtain highly dense nanofibrils. After the transformation into a thin, paper-sheet form through a casting process, the homogenized bacterial cellulose (HBC) resulting from HPH was compared with the normally agitated bacterial cellulose (BC) pulp and decorated with silver nanoparticles (AgNPs) to produce plasmonic papers, for further application as surface-enhanced Raman scattering (SERS) substrate. Read More

Methods Mol Biol 2021 ;2261:55-72

Department of Biochemistry and Molecular Biology, University of Southern Denmark, Odense, Denmark.

Posttranslational modifications (PTMs) such as phosphorylation, acetylation, and glycosylation are an essential regulatory mechanism of protein function and interaction, and they are associated with a wide range of biological processes. Since most PTMs alter the molecular mass of a protein, mass spectrometry (MS) is the ideal analytical tool for studying various PTMs. However, PTMs are often present in substoichiometric levels, and therefore their unmodified counterpart often suppresses their signal in MS. Read More