J Am Acad Psychiatry Law 2020 12;48(4):431-435
Dr. Dike is Medical Director, Office of the Commissioner, Connecticut Department of Mental Health and Addiction Services and Associate Professor of Psychiatry, Law and Psychiatry Division, Yale University School of Medicine.
World J Clin Cases 2020 Oct;8(19):4624-4632
Department of Gastroenterology, West China Hospital, Sichuan University, Chengdu 610041, Sichuan Province, China.
Background: Esophageal carcinosarcoma, usually presenting as a pedunculated polypoid mass, is a rare malignancy with coexisting sarcomatoid and carcinomatous components. Its imaging and endoscopic characteristics are similar to those of leiomyosarcoma, liposarcoma and so forth. The diagnosis needs histological confirmation. Read More
Org Lett 2020 Oct 5;22(20):8111-8115. Epub 2020 Oct 5.
Laboratori de Quı́mica Orgànica, Facultat de Farmàcia, IBUB, Universitat de Barcelona, Av. Joan XXIII s/n, 08028-Barcelona, Spain.
The intermolecular reductive radical coupling of aldehydes with nonactivated alkenes, employing metal hydride atom transfer (MHAT) catalysis with a combination of Fe and Fe salts, is described. This constitutes the first use of aldehydes as viable acceptor groups in MHAT reactions. The insights gained in this study led to the reexamination of the previously reported intramolecular version of the reaction, and the addition of Fe salts allowed the development of a more efficient second-generation approach. Read More
J Cardiothorac Surg 2020 Mar 26;15(1):52. Epub 2020 Mar 26.
Department of Thoracic Surgery, Changhai Hospital, The Second Military Medical University, No. 168 Changhai Road, Shanghai, 200433, China.
Background: Esophageal squamous cell carcinoma with tumor thrombus in the arch of the azygos vein has not been reported to date. Neoadjuvant chemotherapy can decrease the stage in patients with advanced preoperative tumor staging, regaining surgical opportunities and significantly prolonging progression-free survival and overall survival. Herein, we present a case of esophageal squamous cell carcinoma accompanied by tumor thrombus in the arch of the azygos vein, and the patient underwent radical surgery after neoadjuvant chemotherapy. Read More
Hastings Cent Rep 2019 03;49(2):6-8
Evidence-based medicine has become both the mantra of clinical practice and the dominant contemporary approach to patient care. Gordon Guyatt et al. first proposed applying the concept to medical education in the early 1990s, arguing for training that "de-emphasizes intuition, unsystematic clinical experience, and pathophysiologic rationale" in favor of "examination of evidence from clinical research"; over the following twenty-five years, nearly every medical school and residency program in the United States incorporated these methods into its training. Read More