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Food Chem 2021 Mar 8;354:129516. Epub 2021 Mar 8.

School of Food Science and Biotechnology, Zhejiang Gongshang University, Hangzhou 310018, People's Republic of China. Electronic address:

In this work, the β-lactoglobulin/gum arabic (β-Lg-GA) complexes were prepared to encapsulate epigallocatechin gallate (EGCG), forming β-Lg-GA-EGCG complex nanoparticles with an average particle size of 133 nm. The β-Lg-GA complexes exhibited excellent encapsulation efficiency (84.5%), and the antioxidant performance of EGCG in vitro was improved after encapsulation. Read More

Adv Healthc Mater 2021 Mar 9:e2002249. Epub 2021 Mar 9.

Department of Rheumatology and Immunology, Institute of Translational Medicine, The Affiliated Drum Tower Hospital of Nanjing University Medical School, Nanjing, 210008, China.

Stratagems of drug delivery are important for disease treatment and other biomedical areas. In this study, a novel stratagem is presented for versatile and controllable drug delivery by integrating photoresponsive drug delivery microspheres (PDDMs) into pyramid microneedle (MN) arrays. The PDDMs, containing black-phosphorus (BP) and poly (N-isopropylacrylamide) (pNIPAM), are generated by a flexible capillary microfluidic method. Read More

Biotechnol Adv 2021 May-Jun;48:107727. Epub 2021 Mar 5.

Beijing Engineering and Technology Research Center of Food Additives, Beijing Technology & Business University (BTBU), Beijing 100048, China.

Conventional liposomes still face many challenges associated with the poor physical and chemical stability, considerable loss of encapsulated cargo, lack of stimulus responsiveness, and rapid elimination from blood circulation. Integration of versatile functional biopolymers has emerged as an attractive strategy to overcome the limitation of usage of liposomes. This review comprehensively summarizes the most recent studies (2015-2020) and their challenges aiming at the exploration of biopolymer-liposome hybrid systems, including surface-modified liposomes, biopolymer-incorporated liposomes, guest-in-cyclodextrin-in-liposome, liposome-in-hydrogel, liposome-in-film, and liposome-in-nanofiber. Read More

PLoS One 2021 25;16(2):e0247171. Epub 2021 Feb 25.

Department of Biological and Agricultural Engineering, University of California, Davis, CA, United States of America.

Alginates gel rapidly under ambient conditions and have widely documented potential to form protective matrices for sensitive bioactive cargo. Most commonly, alginate gelation occurs via calcium mediated electrostatic crosslinks between the linear polyuronic acid polymers. A recent breakthrough to form crosslinked alginate microcapsules (CLAMs) by in situ gelation during spray drying ("CLAMs process") has demonstrated applications in protection and controlled delivery of bioactives in food, cosmetics, and agriculture. Read More

Colloids Surf B Biointerfaces 2021 Apr 14;200:111526. Epub 2021 Jan 14.

Food Technology Institute, Faculty of Chemical Engineering, National University of Litoral, 1 de Mayo 3250, 3000, Santa Fe, Argentina.

Nanostructured emulsions have a significant potential for encasing, transport and delivery of hydrophilic and lipophilic nutraceuticals and other bioactive compounds by providing enhanced stability and functionality in food and pharmaceutical applications. As highlighted in recent researches, essential fatty acids (EFA) and oils (EO), antioxidants, vitamins, minerals, pro and prebiotics, and co-enzymes, are common bioactives encapsulated in nanoscale delivery systems in order to protect them from degradation during processing and storage, and to improve bioavailability after their consumption. Nanoemulsions (NEs) as delivery systems for nutraceuticals comprise either oil-in-water (O/W) or water-in-oil (W/O) biphasic dispersion with nano-sized droplets, which are stabilized through an active surfactant. Read More