Afr J Biotechnol 2019 30;18(29). Epub 2019 Sep 30.
Section of Crop and Ecosystem Sciences, Department of Plant Sciences/MS1, University of California, 1 Shields Avenue, Davis, CA 95616-8780, USA.
Front Plant Sci 2022 23;13:882655. Epub 2022 May 23.
Chengdu Institute of Biology, Chinese Academy of Sciences, Chengdu, China.
Spike compactness (SC) and length (SL) are the components of spike morphology and are strongly related to grain yield in wheat ( L.). To investigate quantitative trait loci (QTL) associated with SC and SL, a recombinant inbred lines (RIL) population derived from the cross of Bailangmai (BLM, a Tibet landrace) and Chuanyu 20 (CY20, an improved variety) was employed in six environments. Read More
PLoS One 2022 3;17(6):e0269558. Epub 2022 Jun 3.
Institute of Life Sciences, Nalco Square, Chandrasekharpur, Bhubaneswar, India.
Otosclerosis (OTSC) is the primary form of conductive hearing loss characterized by abnormal bone remodelling within the otic capsule of the human middle ear. A genetic association of the RELN SNP rs3914132 with OTSC has been identified in European population. Previously, we showed a trend towards association of this polymorphism with OTSC and identified a rare variant rs74503667 in a familial case. Read More
Acta Otolaryngol 2022 May 31;142(5):448-453. Epub 2022 May 31.
Institute of Otolaryngology, Chinese PLA General Hospital, Beijing, China.
Background: To date, seven mutations have been reported in families with autosomal dominant non-syndromic hearing loss worldwide. All the mutations cause exon 8 skipping at the mRNA level, that led to the protein truncated and the protein could exert a gain of ototoxic function.Objective: In this study, we found an autosomal-dominant non-syndromic hearing loss Chinese pedigree which spanned four generations and comprised 43 members. Read More
Comput Struct Biotechnol J 2022 14;20:2332-2337. Epub 2022 May 14.
College of Plant Science and Technology, Huazhong Agricultural University, Wuhan 430070, China.
Although methodologies and software packages for bulked segregant analysis (BSA) are well established, it is difficult to detect extremely over-dominant and small-effect genes for quantitative traits in F population. To address this issue, we proposed a combinatorial strategy to identify all types of quantitative trait loci (QTLs) using extreme phenotype individuals in F. To popularize this strategy, we developed an R software package dQTG. Read More
J Affect Disord 2022 08 2;310:96-105. Epub 2022 May 2.
Department of Molecular and Cellular Physiology, Graduate School of Medicine, University of the Ryukyus, Okinawa, Japan. Electronic address:
Background: The etiology of bipolar disorder (BD) is poorly understood. Considering the complexity of BD, pedigree-based sequencing studies focusing on haplotypes at specific loci may be practical to discover high-impact risk variants. This study comprehensively examined the haplotype sequence at 1p36-35 BD and recurrent depressive disorder (RDD) susceptibility loci. Read More