Effects of Interval Jump Rope Exercise Combined with Dark Chocolate Supplementation on Inflammatory Adipokine, Cytokine Concentrations, and Body Composition in Obese Adolescent Boys.

Nutrients 2020 Sep 30;12(10). Epub 2020 Sep 30.

Department of Health and Human Performance, Marymount University, Arlington, VA 22207, USA.

We examined the effects of six weeks of dark chocolate supplementation combined with interval jump rope exercise (JRE) on inflammatory cytokines, adipokines, and body composition in obese adolescent boys. Forty-eight obese adolescent boys (age  = 15.4  ±  1.1 years and body mass index  =  32.2  ±  2.4 kg/m) were randomly assigned into one of four groups: JRE + white chocolate (JW; = 13), JRE + dark chocolate supplementation (JD; = 13), dark chocolate supplementation (DS; = 12), or control (C; = 12). Participants in JW and JD groups performed JRE for three times per week for six weeks. Participants in the DS and JD groups consumed 30 g of dark chocolate containing 83% of cocoa. Body composition, pro-inflammatory cytokines ((hs-CRP, TNF-α, IL-6), adipokines (leptin, resistin, RBP-4, chemerin, MCP-1), and anti-inflammatory adipokines (irisin, adiponectin)) were evaluated prior to and after the intervention trials. All three intervention trials significantly ( < 0.05) decreased body mass, waist-hip ratio, fat mass, hs-CRP, TNF-α, IL-6, leptin, resistin, RBP-4, and MCP-1, and increased irisin and adiponectin concentrations. The improvements in these parameters were greater in the JD group, and additionally, chemerin concentrations decreased only in the JD group. JD enhanced adiponectin concentrations and decreased IL-6 concentrations compared to C. Moreover, JD significantly reduced chemerin concentrations, an effect not observed in any of the other interventions. We demonstrated that dark chocolate supplementation potentiated JRE-induced decreases in body mass, WHR, FM, hs-CRP, TNF-α, IL-6, leptin, resistin, RBP-4, and MCP-1, chemerin as well as increases irisin and adiponectin concentrations in obese adolescent boys. Therefore, JRE combined with dark chocolate supplementation could be a beneficial in reducing obesity-induced inflammation in adolescent boys.

Download full-text PDF

Source
http://dx.doi.org/10.3390/nu12103011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7600985PMC
September 2020

Publication Analysis

Top Keywords

dark chocolate
28
chocolate supplementation
24
adolescent boys
20
obese adolescent
16
adiponectin concentrations
12
body composition
12
body mass
12
resistin rbp-4
12
hs-crp tnf-α
12
leptin resistin
12
irisin adiponectin
12
tnf-α il-6
12
composition obese
8
chemerin concentrations
8
il-6 leptin
8
rbp-4 mcp-1
8
intervention trials
8
participants groups
8
concentrations decreased
8
chocolate
8

Similar Publications